Evidence map›Paper›PMID 36613507›Full record

ReviewInternational journal of molecular sciences2022

Skin-Derived ABCB5

Elke Niebergall-Roth, Natasha Y Frank, Christoph Ganss, Markus H Frank, Mark A Kluth

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. E2F2 inhibits hippocampal neurogenesis in poststroke depression rats via the miR-1290/CBR1 axis.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  2. Utilization of Stem Cells in Medicine: A Narrative Review.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Elke Niebergall-RothTICEBA GmbH, 69120 Heidelberg, Germany.
Natasha Y FrankDepartment of Medicine, VA Boston Healthcare System, Boston, MA 02132, USA.
Christoph GanssTICEBA GmbH, 69120 Heidelberg, Germany.ORCID 0000-0003-0396-6591
Markus H FrankHarvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-1312-0488
Mark A KluthTICEBA GmbH, 69120 Heidelberg, Germany.ORCID 0000-0003-0764-4645
Rheacell (Germany) · DEBrigham and Women's Hospital · USEdith Cowan University · AU

Funding

Stem Cell Integral Membrane Transporter ABCB5 and Dermal RegenerationP01AG071463 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Markus H. Frank · 2022 to 2026
$13.6M
ABCB5-positive stem cells for LSCD therapyR01EY025794 · NEI · BOSTON CHILDREN'S HOSPITAL · PI NATASHA Y FRANK, Markus H. Frank · 2016 to 2026
$6.1M
Multipotent ABCB5-positive cell therapeutics for corneal diseaseR24EY028767 · NEI · BRIGHAM AND WOMEN'S HOSPITAL · PI FRANK, MARKUS H., FRANK, NATASHA Y · 2018 to 2022
$5.9M
Skin-Intrinsic Immunosuppressive Mesenchymal Stem Cells and aGVHDR01HL161087 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI FRANK, MARKUS H., FRANK, NATASHA Y · 2022 to 2025
$1.7M
NEI NIH HHS R01 EY025794NEI NIH HHS R24 EY028767NEI NIH HHS R24EY028767NEI NIH HHS RO1EY025794NHLBI NIH HHS 1R01HL161087NHLBI NIH HHS R01 HL161087NIA NIH HHS P01 AG071463
6 · The paper itself

Abstract

The ATP-binding cassette superfamily member ABCB5 identifies a subset of skin-resident mesenchymal stem cells (MSCs) that exhibit potent immunomodulatory and wound healing-promoting capacities along with superior homing ability. The ABCB5

Indexed as

Epidermolysis Bullosa DystrophicaMesenchymal Stem CellsATP Binding Cassette Transporter, Subfamily BGermanyHumansUnited StatesABCB5 protein, humanATP Binding Cassette Transporter, Subfamily BABCB5advanced-therapy medicinal productangiogenesiscell therapychronic woundepidermolysis bullosaimmunomodulationinflammationmesenchymal stem cellswound healing

Identifiers

PMID36613507
PMCPMC9820160
OpenAlexW4313467575

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.