Evidence map›Paper›PMID 36613388›Full record

ArticleFoods (Basel, Switzerland)2022

Effects of Chrysoeriol on Adipogenesis and Lipolysis in 3T3-L1 Adipocytes.

Jinhee Song, Hana Lee, Huijin Heo, Junsoo Lee, Younghwa Kim

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Animal cells and systems · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jinhee SongDepartment of Food Science and Biotechnology, Chungbuk National University, Cheongju 28644, Republic of Korea.
Hana LeeDepartment of Food Science and Biotechnology, Chungbuk National University, Cheongju 28644, Republic of Korea.ORCID 0000-0002-4059-4195
Huijin HeoDepartment of Food Science and Biotechnology, Chungbuk National University, Cheongju 28644, Republic of Korea.ORCID 0000-0003-1117-4068
Junsoo LeeDepartment of Food Science and Biotechnology, Chungbuk National University, Cheongju 28644, Republic of Korea.ORCID 0000-0001-5557-4229
Younghwa KimDepartment of Food Science and Biotechnology, Kyungsung University, Busan 48434, Republic of Korea.ORCID 0000-0003-4186-887X
Chungbuk National University · KRKyungsung University · KR

Funding

Busan metropolitan City and Busan Institute for Talent & Lifelong Education 2022
6 · The paper itself

Abstract

We examined the effect of chrysoeriol on adipogenesis and lipolysis and elucidated the underlying molecular mechanisms. Chrysoeriol inhibited fat deposition in adipocytes. Treatment with chrysoeriol suppressed the expression of peroxisome proliferator-activated receptor γ, fatty acid synthase, fatty acid-binding protein, CCAAT/enhancer-binding proteins (C/EBP) α, C/EBPβ, and sterol regulatory element-binding protein-1. In addition, chrysoeriol significantly elevated the activation of 5'-adenosine monophosphate-activated protein kinase. Moreover, chrysoeriol increased free glycerol and fatty acid levels and promoted lipolysis in adipocytes. Overexpression of adipose triglyceride lipase and hormone-sensitive lipase by chrysoeriol led to increased lipolysis in 3T3-L1 adipocytes. Taken together, chrysoeriol showed anti-adipogenic and lipolytic properties in adipocytes.

Indexed as

adipocytesadipogenesisAMPK pathwaychrysoeriollipolysis

Identifiers

PMID36613388
PMCPMC9818938
OpenAlexW4313388777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.