Evidence map›Paper›PMID 36613272›Full record

ReviewFoods (Basel, Switzerland)2022

Natural Deep Eutectic Solvents (NADESs) Combined with Sustainable Extraction Techniques: A Review of the Green Chemistry Approach in Food Analysis.

Ciro Cannavacciuolo, Stefania Pagliari, Jessica Frigerio, Chiara Maria Giustra, Massimo Labra, Luca Campone

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 186 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Green Extraction of Phenolic Compounds from Blueberry (Antioxidants (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ciro CannavacciuoloDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, I-20126 Milano, Italy.ORCID 0000-0001-8316-2360
Stefania PagliariDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, I-20126 Milano, Italy.ORCID 0000-0002-1381-042X
Jessica FrigerioDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, I-20126 Milano, Italy.
Chiara Maria GiustraDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, I-20126 Milano, Italy.
Massimo LabraDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, I-20126 Milano, Italy.ORCID 0000-0003-1065-5804
Luca CamponeDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, I-20126 Milano, Italy.ORCID 0000-0002-4729-2384
University of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Usual extraction processes for analyzing foods, supplements, and nutraceutical products involve massive amounts of organic solvents contributing to a negative impact on the environment and human health. In recent years, a new class of green solvents called natural deep eutectic solvents (NADES) have been considered a valid alternative to conventional solvents. Compared with conventional organic solvents, NADES have attracted considerable attention since they are sustainable, biodegradable, and non-toxic but also are easy to prepare, and have low production costs. Here we summarize the major aspects of NADEs such as the classification, preparation method physicochemical properties, and toxicity. Moreover, we provide an overview of novel extraction techniques using NADES as potential extractants of bioactive compounds from foods and food by-products, and application of NADEs in food analysis. This review aims to be useful for the further development of NAES and for broadening the knowledge of these new green solvents in order to increase their use for the extraction of bioactive compounds and in food analysis.

Indexed as

food analysisgreen extractionNADESnatural deep eutectic solvents

Identifiers

PMID36613272
PMCPMC9818194
OpenAlexW4312175218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.