Evidence map›Paper›PMID 36612834›Full record

ArticleInternational journal of environmental research and public health2022

Are

Zhuo Sun, Paweł Cięszczyk, Ewelina Lulińska, Magdalena Dzitkowska-Zabielska, Monika Johne, Kinga Humińska-Lisowska, Monika Michałowska-Sawczyn, Krzysztof Ficek, Agata Leońska-Duniec, Andrzej Mastalerz and 2 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. International journal of molecular sciences · 2025
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhuo SunFaculty of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Paweł CięszczykFaculty of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Ewelina LulińskaFaculty of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Magdalena Dzitkowska-ZabielskaFaculty of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.ORCID 0000-0002-7375-9814
Monika JohneFaculty of Physical Education, Jozef Pilsudski University of Physical Education in Warsaw, 00-809 Warsaw, Poland.ORCID 0000-0002-7066-8909
Kinga Humińska-LisowskaFaculty of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.ORCID 0000-0003-0034-0809
Monika Michałowska-SawczynFaculty of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Krzysztof FicekFaculty of Physiotherapy, The Jerzy Kukuczka Academy of Physical Education in Katowice, 40-065 Katowice, Poland.ORCID 0000-0002-3027-9984
Agata Leońska-DuniecFaculty of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.ORCID 0000-0001-6787-3760
Andrzej MastalerzFaculty of Physical Education, Jozef Pilsudski University of Physical Education in Warsaw, 00-809 Warsaw, Poland.
Arkadiusz JanczykCenter for Physiotherapy, Military Unit No. 6021, 01-001 Warsaw, Poland.
Sawczuk MarekInstitute of Physical Culture Sciences, University of Szczecin, 70-453 Szczecin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the risk factors and etiology of ACL ruptures (anterior cruciate ligament) is crucial due to the injury’s high occurrence, significant financial cost to the healthcare sector, and clinical consequences. In this study, we investigated the hypothesis that rs11784270 A/C and rs6577958 C/T SNPs (single gene polymorphism) within COL22A1 are associated with ACL ruptures (ACLR) in Polish soccer players. Methods: 228 athletes with ACLR (157 male, age 26 ± 4, 71 female, age 26 ± 6) and 202 control athletes (117 male, age 26 ± 6, 85 female, age 29 ± 2) engaged in the study. The buccal cell swabs were genotyped using TaqMan® pre-designed SNP genotyping assays, following the manufacturer’s recommendations. The R program and SNPassoc package were used to determine the genotype and allele frequency distributions under the various inheritance models (co-dominant, dominant, recessive, and over-dominant). Further, p-values of <0.05 were considered statistically significant. We found no association between the analyzed polymorphisms and the risk of non-contact ACL ruptures in any of the studied models. Although the genetic variants investigated in this study were not associated with the risk of non-contact ACL ruptures, we assumed that the COL22A1 gene remains a candidate for further investigations in musculoskeletal injuries.

Indexed as

Anterior Cruciate Ligament InjuriesSoccerAdultAnterior Cruciate LigamentAthletesFemaleHumansMalePolandPolymorphism, Single NucleotideRuptureYoung AdultACLathletesCOL22A1 geneinjury

Identifiers

PMID36612834
PMCPMC9819041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.