Evidence map›Paper›PMID 36612831›Full record

ArticleInternational journal of environmental research and public health2022

Cost-Effectiveness and Cost-Utility of Palbociclib versus Ribociclib in Women with Stage IV Breast Cancer: A Real-World Data Evaluation.

Nour Hisham Al-Ziftawi, Mohammed Fasihul Alam, Shereen Elazzazy, Asrul Akmal Shafie, Anas Hamad, Mohamed Izham Mohamed Ibrahim

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Cell cycle plasticity underlies fractional resistance to palbociclib in ER+/HER2- breast tumor cells.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nour Hisham Al-ZiftawiClinical Pharmacy and Practice Department, College of Pharmacy, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0002-4152-9870
Mohammed Fasihul AlamDepartment of Public Health, College of Health Sciences, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Shereen ElazzazyPharmacy Department, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha P.O. Box 3050, Qatar.ORCID 0000-0002-0017-4401
Asrul Akmal ShafieSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, Malaysia.ORCID 0000-0002-5629-9270
Anas HamadClinical Pharmacy and Practice Department, College of Pharmacy, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-8606-8521
Mohamed Izham Mohamed IbrahimClinical Pharmacy and Practice Department, College of Pharmacy, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-9757-3574
Qatar University · QANational Center for Cancer Care and Research · QAUniversiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Palbociclib and ribociclib are indicated in the first-line treatment of hormonal-receptor-positive HER-2 negative (HR+/HER-2 negative) advanced breast cancer. Despite their clinical benefit, they can increase healthcare expenditure. Yet, there are no comparative pharmacoeconomic evaluations for them in developing countries, the Middle East, or Gulf countries. This study compared the cost-effectiveness of palbociclib and ribociclib in Qatar. A 10-year within-cycle-corrected Markov's model was developed using TreeAge Pro

Indexed as

Breast NeoplasmsAminopyridinesAntineoplastic Combined Chemotherapy ProtocolsCost-Benefit AnalysisFemaleHumansPiperazinesPurinesPyridinesAminopyridinespalbociclibPiperazinesPurinesPyridinesribociclibadvanced breast cancercost-effectivenesscost-savingcost-utilitycyclin-dependent-kinase 4/6 inhibitors

Identifiers

PMID36612831
PMCPMC9819837
OpenAlexW4313327140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.