ReviewInternational journal of environmental research and public health2022
Functional Dentition, Chronic Periodontal Disease and Frailty in Older Adults-A Narrative Review.
Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Evaluation of the effect of omega-3 fatty acids supplementation as an adjunct to non-surgical periodontal therapy: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Age-Related Differences in Oral Microbiota Among Obese Patients with Periodontitis: A Systematic Review.Nutrients · 2026Pooled it
- Association between oral health status and frailty in older adults: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Effect of oral functional exercise combined with psychological intervention on oral frailty in older adults.BMC oral health · 2025Trial
- Estimating the Causal Effect of Tooth Loss on the Critical Outcome of COVID-19.JDR clinical and translational research · 2026Article
- Global, Regional, and National Burden of Oral Diseases in Older Adults Aged 65 Years And Over.International dental journal · 2026Article
- Oral frailty and activities of daily living among community-dwelling older adults: the indirect association of nutritional status.Frontiers in public health · 2026Observational
- Comprehensive Strategies for Preventive Periodontal Care in Older Adults.Geriatrics (Basel, Switzerland) · 2025Review
- Association between tooth loss and geriatric syndromes in older adults: a cohort study from a rural area in eastern China.Aging clinical and experimental research · 2025Article
- Research status and hotspots of oral frailty in older adults: a bibliometric analysis from 2013 to 2024.Frontiers in oral health · 2025Article
- Impact of dental operative microscopes on precision in minimally invasive dental restoration procedures.American journal of translational research · 2024Article
- Association between periodontal health status and quality of life: a cross-sectional study.Frontiers in oral health · 2024Article
- Diet, Nutrition, and Oral Health in Older Adults: A Review of the Literature.Dentistry journal · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe likelihood of experiencing the impact of chronic disease rises with age, and cumulative functional deficits over time increase the risk of frailty in older adults. The exact causes of frailty are not clear, and research is needed to identify appropriate intervention measures to reduce risk of developing frailty in old age.
objectiveTo review the evidence on the relationship between frailty, dental status and chronic periodontitis and to determine if improvements in oral health of older adults can contribute to reversal of frailty.
resultsThe oral cavity is the entry point to the gastro-intestinal tract, and natural teeth facilitate efficient mastication of food prior to swallowing and subsequent digestion. The loss of natural teeth, which is gradual and cumulative over the life course, is associated with diminished nutritional intake, especially in older adults. Furthermore, chronic periodontitis has been postulated as a risk factor for frailty. The evidence supporting a strong relationship between oral health status and frailty is not clearcut. Cross sectional studies suggest an association with missing teeth and chronic periodontal inflammation. However, there are very few longitudinal studies and accordingly, it is not currently possible to claim a causal relationship. As yet, there is no evidence to suggest that improvements in oral health contribute to reversal of frailty.
conclusionLongitudinal studies with robust designs are required to better inform the relationship across functional dentition, chronic periodontitis and frailty in older adults.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.