Evidence map›Paper›PMID 36612726›Full record

ArticleInternational journal of environmental research and public health2022

Ten-Year Probabilities of Death Due to Cancer and Cardiovascular Disease among Breast Cancer Patients Diagnosed in North-Eastern Spain.

Ramon Clèries, Alberto Ameijide, Maria Buxó, Mireia Vilardell, José Miguel Martínez, Rebeca Font, Rafael Marcos-Gragera, Montse Puigdemont, Gemma Viñas, Marià Carulla and 4 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ramon ClèriesPla Director d'Oncología, Av Gran Vía 199-203, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0002-3637-4747
Alberto AmeijideTarragona Cancer Registry, Epidemiology and Cancer Prevention Service, Hospital Universitari Sant Joan de Reus, IISPV, 43204 Reus, Spain.
Maria BuxóGirona Biomedical Research Institute, IDIBGI, C/Dr. Castany s/n, Edifici M2, Parc Hospitalari Martí i Julià, 17190 Salt, Spain.ORCID 0000-0001-7165-7737
Mireia VilardellIndependent Researcher, 08700 Barcelona, Spain.
José Miguel MartínezStatistics and Operational Research Department, Universitat Politècnica de Catalunya, EDIFICI H, Diagonal 647, 08028 Barcelona, Spain.
Rebeca FontPla Director d'Oncología, Av Gran Vía 199-203, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.
Rafael Marcos-GrageraGirona Biomedical Research Institute, IDIBGI, C/Dr. Castany s/n, Edifici M2, Parc Hospitalari Martí i Julià, 17190 Salt, Spain.ORCID 0000-0001-9824-3657
Montse PuigdemontGirona Cancer Registry, Epidemiology Unit, Pla Director d'Oncologia, Institut Català d'Oncología, Group for Descriptive Epidemiology, Genetics and Cancer Prevention, Girona-IDIBGI, 17005 Girona, Spain.ORCID 0000-0001-9961-3699
Gemma ViñasMedical Oncology Service, Catalan Institute of Oncology, Hospital Universitari de Girona "Doctor Josep Trueta", 17005 Girona, Spain.
Marià CarullaTarragona Cancer Registry, Epidemiology and Cancer Prevention Service, Hospital Universitari Sant Joan de Reus, IISPV, 43204 Reus, Spain.
Josep Alfons EspinàsPla Director d'Oncología, Av Gran Vía 199-203, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.
Jaume GalceranTarragona Cancer Registry, Epidemiology and Cancer Prevention Service, Hospital Universitari Sant Joan de Reus, IISPV, 43204 Reus, Spain.
Ángel IzquierdoGirona Cancer Registry, Epidemiology Unit, Pla Director d'Oncologia, Institut Català d'Oncología, Group for Descriptive Epidemiology, Genetics and Cancer Prevention, Girona-IDIBGI, 17005 Girona, Spain.
Josep Maria BorràsPla Director d'Oncología, Av Gran Vía 199-203, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0001-7330-6308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mortality from cardiovascular disease (CVD), second tumours, and other causes is of clinical interest in the long-term follow-up of breast cancer (BC) patients. Using a cohort of BC patients (N = 6758) from the cancer registries of Girona and Tarragona (north-eastern Spain), we studied the 10-year probabilities of death due to BC, other cancers, and CVD according to stage at diagnosis and hormone receptor (HR) status. Among the non-BC causes of death (N = 720), CVD (N = 218) surpassed other cancers (N = 196). The BC cohort presented a significantly higher risk of death due to endometrial and ovarian cancers than the general population. In Stage I, HR- patients showed a 1.72-fold higher probability of all-cause death and a 6.11-fold higher probability of breast cancer death than HR+ patients. In Stages II-III, the probability of CVD death (range 3.11% to 3.86%) surpassed that of other cancers (range 0.54% to 3.11%). In Stage IV patients, the probability of death from any cancer drove the mortality risk. Promoting screening and preventive measures in BC patients are warranted, since long-term control should encompass early detection of second neoplasms, ruling out the possibility of late recurrence. In patients diagnosed in Stages II-III at an older age, surveillance for preventing late cardiotoxicity is crucial.

Indexed as

Breast NeoplasmsCardiovascular DiseasesEarly Detection of CancerFemaleHumansProbabilitySpainbreast cancercardiovascular diseasecauses of deathhormone receptor statusprobability of deathsecond tumoursstage

Identifiers

PMID36612726
PMCPMC9819018

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.