SynthesisInternational journal of environmental research and public health2022
Human Health Impacts of Residential Radon Exposure: Updated Systematic Review and Meta-Analysis of Case-Control Studies.
Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Exposure to radon and ambient particle radioactivity during pregnancy and adverse maternal, fetal and perinatal outcomes: The current literature and potential mechanisms.Environmental research · 2024Pooled it
- Indoor Radon Concentrations and Hematologic Traits in the Women's Health Initiative.Epidemiology (Cambridge, Mass.) · 2026Article
- Radon balneotherapy in rheumatologic diseases: potential mechanisms and implications for cardiovascular autonomic control and inflammation.Clinical rheumatology · 2026Review
- Assessing historical residential radon exposure using a glass-based surface trap method in low radon level areas: a pilot study.Journal of radiological protection : official journal of the Society for Radiological Protection · 2026Article
- Global trends and projections of lung cancer attributable to residential radon exposure, 1990-2050.BMC cancer · 2026Article
- Rural Public Library Lending Programs Advance Population-Based Radon Testing.American journal of health promotion : AJHP · 2026Article
- Radon gas mapping for environmental assessment in Dessie, Ethiopia.Scientific reports · 2025Article
- Seasonal variation and structural influences on indoor radon exposure in residential buildings of Khuzestan Province.Scientific reports · 2025Article
- Systematic Review and Meta-Analysis of Inflammatory Biomarkers in Individuals Exposed to Radon.Biomedicines · 2025Review
- Serum biomarkers associated with health impacts of high residential radon exposure: a metabolomic pilot study.Scientific reports · 2025Article
- Temporal trends in lung cancer and radon gas exposure: an ecological study in Rio Grande do Sul.Ecancermedicalscience · 2025Article
- Indoor radon exposure: A systematic review of radon-induced health risks and evidence quality using GRADE approach.Heliyon · 2024Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Environmental Pollution and Risk of Childhood Cancer: A Scoping Review of Evidence from the Last Decade.International journal of molecular sciences · 2024Article
- Article
- Lung cancer in patients who have never smoked - an emerging disease.Nature reviews. Clinical oncology · 2024Review
- Trends in childhood leukemia incidence in urban countries and their relation to environmental factors, including space weather.Frontiers in public health · 2024Article
- Radon exposure risks among residents proximal to gold mine tailings in Gauteng Province, South Africa: a cross-sectional preliminary study protocol.Frontiers in public health · 2024Article
- Experimental Setups for In Vitro Studies on Radon Exposure in Mammalian Cells-A Critical Overview.International journal of environmental research and public health · 2023Review
- Radon exposure: a major cause of lung cancer in nonsmokers.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the impact of residential radon exposure on human cancers (i.e., lung cancer and childhood leukemia) through a systematic review and meta-analysis of case−control studies. A total of 9724 articles obtained from electronic databases were assessed; however, only 55 case−control studies were eligible after manually screening and eliminating unnecessary studies. The causal associations were addressed by determining the meta-analysis’s estimated size effects (i.e., ORs/RRs) of the meta-analysis. Residential radon was revealed to significantly increase the incidence of lung cancer and childhood leukemia with pooled ORs of 1.38 [1.19; 1.60] (I2 = 90%; p < 0.00001) and 1.43 [1.19; 1.72] (I2 = 0% and p = 0.51), respectively. In addition, subgroup analyses were performed to reduce the heterogeneity of the initial meta-analyses. The results provided strong evidence that inhaling radon in the indoor environments is closely associated with the development of lung cancer and childhood leukemia in patients living in Europe and areas with high radon levels (≥100 Bq/m3).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.