Evidence map›Paper›PMID 36612415›Full record

ArticleInternational journal of environmental research and public health2022

Human Microbiome Mixture Analysis Using Weighted Quantile Sum Regression.

Shoshannah Eggers, Moira Bixby, Stefano Renzetti, Paul Curtin, Chris Gennings

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Relevance and challenges of exposome studies for environmental health research.Environmental health : a global access science source · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Prenatal Lead Exposure is Negatively Associated with the Gut Microbiome in Childhood.medRxiv : the preprint server for health sciences · 2023
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Shoshannah EggersDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, Box 1057, New York, NY 10029, USA.ORCID 0000-0002-4321-9219
Moira BixbyDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, Box 1057, New York, NY 10029, USA.
Stefano RenzettiDepartment of Medical-Surgical Specialties, Radiological Sciences and Public Health, Università degli Studi di Brescia, Piazza del Mercato, 15, 25121 Brescia, Italy.ORCID 0000-0002-4467-765X
Paul CurtinDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, Box 1057, New York, NY 10029, USA.ORCID 0000-0003-3749-3868
Chris GenningsDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, Box 1057, New York, NY 10029, USA.ORCID 0000-0002-6058-5907
Icahn School of Medicine at Mount Sinai · USUniversity of Brescia · IT

Funding

Statistical Services and Methods Development ResourceU2CES026555 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GENNINGS, CHRIS · 2015 to 2025
$26.4M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Robert O Wright · 2014 to 2026
$21.3M
Research Training Program in Pediatric ExposomicsT32HD049311 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2007 to 2026
$7.4M
Early life metal exposure, the gut microbiome, and neurodevelopment in childhoodK99ES032884 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI EGGERS, SHOSHANNAH IYLENE · 2022 to 2023
$210k
NICHD NIH HHS T32 HD049311NIEHS NIH HHS K99 ES032884NIEHS NIH HHS P30 ES023515NIEHS NIH HHS P30ES023515NIEHS NIH HHS U2C ES026555NIEHS NIH HHS U2CES026555
6 · The paper itself

Abstract

Studies of the health effects of the microbiome often measure overall associations by using diversity metrics, and individual taxa associations in separate analyses, but do not consider the correlated relationships between taxa in the microbiome. In this study, we applied random subset weighted quantile sum regression with repeated holdouts (WQS

Indexed as

Gastrointestinal MicrobiomeMicrobiotaBody Mass IndexFecesHumansObesityhuman microbiomemicrobiome analysismixture analysisweighted quantile sum regression

Identifiers

PMID36612415
PMCPMC9819204
OpenAlexW4313511290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.