Evidence map›Paper›PMID 36612293›Full record

ArticleCancers2022

PSMA-RLT in Patients with Metastatic Hormone-Sensitive Prostate Cancer: A Retrospective Study.

Amina Banda, Bastiaan M Privé, Youssra Allach, Maike J M Uijen, Steffie M B Peters, Cato C Loeff, Martin Gotthardt, Constantijn H J Muselaers, J Alfred Witjes, Inge M van Oort and 12 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. The role of PSMA-based radioligand therapy in hormone-sensitive prostate cancer.European journal of nuclear medicine and molecular imaging · 2025
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  6. Article
  7. The current status of prostate cancer treatment and PSMA theranostics.Therapeutic advances in medical oncology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 3 countries.

Amina BandaDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0001-8297-3137
Bastiaan M PrivéDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.
Youssra AllachDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.
Maike J M UijenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.
Steffie M B PetersDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.
Cato C LoeffDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.
Martin GotthardtDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.
Constantijn H J MuselaersDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.
J Alfred WitjesDepartment of Medical Oncology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Inge M van OortDepartment of Medical Oncology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
J P Michiel SedelaarDepartment of Medical Oncology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0002-3768-7374
Harm WestdorpDepartment of Urology and Oncology, Radboud Universiteit Medical Center, 6525 GA Nijmegen, The Netherlands.
Niven MehraDepartment of Urology and Oncology, Radboud Universiteit Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0002-4794-1831
Fadi KhreishDepartment of Nuclear Medicine, University of Saarland, D-66421 Homburg, Germany.ORCID 0000-0002-1036-7477
Samer EzziddinDepartment of Nuclear Medicine, University of Saarland, D-66421 Homburg, Germany.ORCID 0000-0003-4110-3375
Amir SabetUniversity Hospital, Department of Nuclear Medicine, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0003-3027-5083
Michael C KreisslDivision of Nuclear Medicine, Department of Radiology and Nuclear Medicine, Magdeburg University Hospital, 39120 Magdeburg, Germany.ORCID 0000-0001-5905-6015
Thomas WinkensClinic for Nuclear Medicine, University Hospital of Jena, 07743 Jena, Germany.ORCID 0000-0002-8958-4801
Philipp SeifertClinic for Nuclear Medicine, University Hospital of Jena, 07743 Jena, Germany.ORCID 0000-0002-3447-4971
Marcel J R JanssenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.
Willemijn A M van GemertDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.
James NagarajahDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0002-3555-0809
Radboud University Nijmegen · NLJena University Hospital · DESaarland University · DEGoethe University Frankfurt · DEUniversity Hospital Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProstate-specific membrane antigen (PSMA)-directed radioligand therapy (RLT) is a novel treatment for patients with castration-resistant prostate cancer (CRPC). Given the mode of action, patients in an earlier disease stage, such as hormone-sensitive prostate cancer (HSPC), are also likely to benefit from [

methodsA retrospective study was performed in patients who received

resultsIn total, 20 patients were included of which 18 patients received

conclusionsIn this small cohort study, PSMA-RLT appeared safe and showed encouraging efficacy for (metastasized) early-stage and hormone-sensitive prostate cancer patients. Prospective studies are awaited and should include long-term follow-up.

Indexed as

Actinium-225early stageLutetium-177prostate cancerPSMA radioligand therapy

Identifiers

PMID36612293
PMCPMC9818570
OpenAlexW4313472254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.