Evidence map›Paper›PMID 36612287›Full record

ArticleCancers2022

Robust Performance of the Novel Research-Use-Only Idylla GeneFusion Assay Using a Diverse Set of Pathological Samples with a Proposed 1-Day Workflow for Advanced NSCLC Evaluation.

Alvaro Leone, Lucia Anna Muscarella, Paolo Graziano, Andrea Tornese, Lucia Rosalba Grillo, Angela Di Lorenzo, Monica Bronzini, Stefania Scarpino, Angelo Sparaneo, Giulio Rossi

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. AccurateInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. A narrative review of methods for the identification ofTranslational lung cancer research · 2023
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alvaro LeoneAnatomic Pathology Unit, San Camillo-Forlanini Hospitals, 00152 Rome, Italy.ORCID 0000-0003-3815-9052
Lucia Anna MuscarellaLaboratory of Oncology, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy.ORCID 0000-0002-1866-8151
Paolo GrazianoUnit of Pathology, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy.ORCID 0000-0001-7066-7896
Andrea TorneseAnatomic Pathology Unit, San Camillo-Forlanini Hospitals, 00152 Rome, Italy.
Lucia Rosalba GrilloAnatomic Pathology Unit, San Camillo-Forlanini Hospitals, 00152 Rome, Italy.
Angela Di LorenzoAnatomic Pathology Unit, San Camillo-Forlanini Hospitals, 00152 Rome, Italy.
Monica BronziniAnatomic Pathology Unit, San Camillo-Forlanini Hospitals, 00152 Rome, Italy.
Stefania ScarpinoDepartment of Clinical and Molecular Medicine, Pathology Unit, St. Andrea University Hospital, University of Rome La Sapienza, 00187 Rome, Italy.
Angelo SparaneoLaboratory of Oncology, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy.
Giulio RossiOperative Unit of Pathologic Anatomy, Department of Oncology, Fondazione Poliambulanza Hospital Institute, 25124 Brescia, Italy.ORCID 0000-0001-8855-1218

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A range of different techniques are available for predictive biomarker testing for non-small-cell lung cancer (NSCLC) clinical management. International guidelines suggest next-generation sequencing (NGS) as the preferred procedure, but other reverse transcriptase-polymerase chain reaction (RT-PCR)-based methods are rapidly evolving. In this study, we evaluated the reliability and accuracy of the Idylla

Indexed as

ALKMETnon-small-cell lung cancerNTRKRETROS1

Identifiers

PMID36612287
PMCPMC9818630

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.