Evidence map›Paper›PMID 36612257›Full record

ArticleCancers2022

Variables Associated with False-Positive PSA Results: A Cohort Study with Real-World Data.

Blanca Lumbreras, Lucy Anne Parker, Juan Pablo Caballero-Romeu, Luis Gómez-Pérez, Marta Puig-García, Maite López-Garrigós, Nuria García, Ildefonso Hernández-Aguado

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Innovations in biomarker stratification for precision oncology.Clinical and experimental medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Blanca LumbrerasDepartment of Public Health, University Miguel Hernández de Elche, 03550 Alicante, Spain.ORCID 0000-0003-1665-0860
Lucy Anne ParkerDepartment of Public Health, University Miguel Hernández de Elche, 03550 Alicante, Spain.ORCID 0000-0002-2362-4057
Juan Pablo Caballero-RomeuDepartment of Urology, University General Hospital of Alicante, 03010 Alicante, Spain.ORCID 0000-0002-5737-6047
Luis Gómez-PérezUrology Department, General University Hospital of Elche, 03203 Elche, Spain.ORCID 0000-0003-1396-0484
Marta Puig-GarcíaDepartment of Public Health, University Miguel Hernández de Elche, 03550 Alicante, Spain.ORCID 0000-0003-3259-9524
Maite López-GarrigósCIBER de Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0001-8440-6558
Nuria GarcíaDepartment of Urology, University General Hospital of Alicante, 03010 Alicante, Spain.
Ildefonso Hernández-AguadoDepartment of Public Health, University Miguel Hernández de Elche, 03550 Alicante, Spain.ORCID 0000-0003-1911-5759

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: There are no real-world data evaluating the incidence of false-positive results. We analyzed the clinical and analytical factors associated with the presence of false-positive results in PSA determinations in practice. (2) Methods: A prospective cohort study of patients with a PSA test was performed in clinical practice. We followed the patients by reviewing their medical records for 2 years or until the diagnosis of PCa was reached, whichever came first. (3) Results: False-positive PSA rate was 46.8% (95% CI 44.2-49.2%) and false-negative PSA rate was 2.8% (95% CI 2-3.5%). Patients aged 61-70 years and those over 70 years were more likely to have a false-positive result than those under 45 years (aOR 2.83, 95% CI 1.06-7.55,

Indexed as

false-positive resultsprostate cancerprostate-specific antigenreal world-data

Identifiers

PMID36612257
PMCPMC9818944

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.