Evidence map›Paper›PMID 36612199›Full record

ArticleCancers2022

Store-Operated Calcium Entry in Breast Cancer Cells Is Insensitive to Orai1 and STIM1 N-Linked Glycosylation.

Jose Sanchez-Collado, Joel Nieto-Felipe, Isaac Jardin, Rajesh Bhardwaj, Alejandro Berna-Erro, Gines M Salido, Tarik Smani, Matthias A Hediger, Jose J Lopez, Juan A Rosado

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Jose Sanchez-ColladoDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.
Joel Nieto-FelipeDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0001-6342-3893
Isaac JardinDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0003-4575-8264
Rajesh BhardwajMembrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, University of Bern, CH-3010 Bern, Switzerland.ORCID 0000-0002-5599-487X
Alejandro Berna-ErroDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0003-1459-6418
Gines M SalidoDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.
Tarik SmaniDepartment of Medical Physiology and Biophysic, Institute of Biomedicine of Sevilla, 41013 Sevilla, Spain.ORCID 0000-0002-1877-7438
Matthias A HedigerMembrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, University of Bern, CH-3010 Bern, Switzerland.ORCID 0000-0003-1946-027X
Jose J LopezDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0002-5234-1478
Juan A RosadoDepartment of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0002-9749-2325
Universidad de Extremadura · ESUniversity of Bern · CHInstituto de Biomedicina de Sevilla · ES

Funding

Agencia Estatal de Investigación PID2019-104084GB-C21Agencia Estatal de Investigación PID2019-104084GB-C22Government of Extremadura GR21008Government of Extremadura IB20007Government of Extremadura TA18011Government of Extremadura TA18054Swiss National Science Foundation 310030_204972Swiss National Science Foundation CRSII5_180326
6 · The paper itself

Abstract

N-linked glycosylation is a post-translational modification that affects protein function, structure, and interaction with other proteins. The store-operated Ca

Indexed as

breast cancer cellsCa2+ entryglycosylationOrai1posttranslational modificationsSTIM1store-operated Ca2+ entry

Identifiers

PMID36612199
PMCPMC9818078
OpenAlexW4313362592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.