Evidence map›Paper›PMID 36612018›Full record

ArticleCancers2022

Effects of Irradiation on Brain Tumors Using MR-Based Electrical Conductivity Imaging.

Ji Ae Park, Youngsung Kim, Jiung Yang, Bup Kyung Choi, Nitish Katoch, Seungwoo Park, Young Hoe Hur, Jin Woong Kim, Hyung Joong Kim, Hyun Chul Kim

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 citations in OpenAlex.

  1. Effect of acupuncture on fatigue in cancer survivors with chronic pain: a secondary analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  2. Clinical Applications of Electrical Conductivity Imaging Using MRI.Journal of magnetic resonance imaging : JMRI · 2026
    Review
  3. Article
  4. Integrating English and Chinese evidence on acupuncture and moxibustion for cancer-related fatigue (CRF): a decade of research and clinical recommendations.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  5. Review
  6. Article
  7. Impact of statin use in head and neck cancer: a nested case-control study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Ji Ae ParkDivision of Applied RI, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.ORCID 0000-0001-6109-802X
Youngsung KimOffice of Strategic R&D Planning (MOTIE), Seoul 06152, Republic of Korea.
Jiung YangDivision of Applied RI, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Bup Kyung ChoiMedical Science Research Institute, Kyung Hee University Hospital, Seoul 02447, Republic of Korea.
Nitish KatochMedical Science Research Institute, Kyung Hee University Hospital, Seoul 02447, Republic of Korea.ORCID 0000-0003-4488-201X
Seungwoo ParkComprehensive Radiation Irradiation Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Young Hoe HurDepartment of Hepato-Biliary-Pancreas Surgery, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.
Jin Woong KimDepartment of Radiology, Chosun University Hospital, Gwangju 61453, Republic of Korea.
Hyung Joong KimMedical Science Research Institute, Kyung Hee University Hospital, Seoul 02447, Republic of Korea.ORCID 0000-0001-7591-9079
Hyun Chul KimDepartment of Radiology, Chosun University Hospital, Gwangju 61453, Republic of Korea.
Chosun University Hospital · KRKorea Institute of Radiological and Medical Sciences · KRKyung Hee University Medical Center · KRChonnam National University · KRMinistry of Trade, Industry and Energy · KR

Funding

National Research Foundation of Korea 2019R1A2C2088573National Research Foundation of Korea 2020R1A2C200790611National Research Foundation of Korea 2020R1I1A3065215National Research Foundation of Korea 2021R1A2C2004299National Research Foundation of Korea 2021R1I1A3050277
6 · The paper itself

Abstract

Ionizing radiation delivers sufficient energy inside the human body to create ions, which kills cancerous tissues either by damaging the DNA directly or by creating charged particles that can damage the DNA. Recent magnetic resonance (MR)-based conductivity imaging shows higher sensitivity than other MR techniques for evaluating the responses of normal tissues immediately after irradiation. However, it is still necessary to verify the responses of cancer tissues to irradiation by conductivity imaging for it to become a reliable tool in evaluating therapeutic effects in clinical practice. In this study, we applied MR-based conductivity imaging to mouse brain tumors to evaluate the responses in irradiated and non-irradiated tissues during the peri-irradiation period. Absolute conductivities of brain tissues were measured to quantify the irradiation effects, and the percentage changes were determined to estimate the degree of response. The conductivity of brain tissues with irradiation was higher than that without irradiation for all tissue types. The percentage changes of tumor tissues with irradiation were clearly different than those without irradiation. The measured conductivity and percentage changes between tumor rims and cores to irradiation were clearly distinguished. The contrast of the conductivity images following irradiation may reflect the response to the changes in cellularity and the amounts of electrolytes in tumor tissues.

Indexed as

brain tumorelectrical conductivityionizing radiationmagnetic resonance imagingradiation therapy

Identifiers

PMID36612018
PMCPMC9817812
OpenAlexW4313466025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.