SynthesisCells2023
Effect of Different Application Modalities on the Bonding Performance of Adhesive Systems to Dentin: A Systematic Review and Meta-Analysis.
Synthesis in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- From Classical Enamel/Dentin Bonding to Self-Adhesive Composites: A Narrative Review of Current Clinical Aspects.Bioengineering (Basel, Switzerland) · 2026Review
- Impact of PVM/MA Copolymer on Dentin Bond Durability.Acta stomatologica Croatica · 2026Article
- Comparative In Vitro Evaluation of Residual Fiber Contamination from Applicators in the Adhesive Interface.The journal of adhesive dentistry · 2026Article
- Toward a Functional and Conceptual Framework for Adhesive Materials: The Role of Etching Technique.Dentistry journal · 2026Review
- Bond preservation in caries-affected dentin restored with acrylamide-based adhesives.Dental materials : official publication of the Academy of Dental Materials · 2025Article
- Bioengineering perspectives on adhesive delivery: performance analysis of dental microapplicators.Frontiers in dental medicine · 2025Article
- Effect of multi-layer applications of self-etch universal bonding agents on the adhesion of resin composite to enamel.Odontology · 2025Article
- Effect of surface treatments and bonding type on elemental composition and bond strength of dentin.Scientific reports · 2024Article
- Ultrasonic activation of adhesive systems increases bond strength and intratubular penetration of resin cement in root dentin subjected to radiation therapy.Clinical oral investigations · 2024Article
- Comparative cell viability of dentin-bonding adhesive systems on human dental pulp stem cells: time-dependent analysis.BMC oral health · 2024Article
- Equivalence study of the resin-dentine interface of internal tunnel restorations when using an enamel infiltrant resin with ethanol-wet dentine bonding.Scientific reports · 2024Article
- A new method of adhesive system application improves the bond strength between fiber post and root dentin.Brazilian dental journal · 2024Article
- Effect of Modified Triple-Layer Application on the Bond Strength of Different Dental Adhesive Systems to Dentin.Journal of functional biomaterials · 2023Article
- Effectiveness of Different Application Modalities on the Bond Performance of Four Polymeric Adhesive Systems to Dentin.Polymers · 2023Article
- The Use of Warm Air for Solvent Evaporation in Adhesive Dentistry: A Meta-Analysis of In Vitro Studies.Journal of functional biomaterials · 2023Review
- The Classification and Selection of Adhesive Agents; an Overview for the General Dentist.Clinical, cosmetic and investigational dentistry · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diverse types of dental adhesives exhibit different cytotoxic outcomes on cells in vitro. Currently, no standard adhesive application technique has so far been decisive for clinicians for better durability of resin-dentin bonds of adhesive systems. The purpose of this study was to systematically review the literature to evaluate the bonding performance of adhesive systems to dentin by using different application modalities. The systematic research strategy was conducted by two reviewers among multiple databases: PubMed, Scopus, Web of Science, Embase, and Scielo. In vitro studies reporting the effects of additional steps for the application of adhesive systems on the bond strength to dentin were selected. Meta-analysis was performed using Review Manager Software version 5.3.5 using the random effects model. The methodological quality of each in vitro study was assessed according to the parameters of a previous systematic review. The electronic research through different databases generated a total of 8318 references. After the examination of titles and abstracts, a total of 106 potentially relevant studies accessed the full-text evaluation phase. After full-text examination, 78 publications were included for the qualitative analysis, and 68 studies were included in the meta-analysis. Regarding the etch-and-rinse adhesive systems, the application modalities that improved the overall bond strength were the application of a hydrophobic resin layer (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.