ArticleCells2022
Repeated Superovulation Accelerates Primordial Follicle Activation and Atresia.
Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Repeated surgical oocyte collection from severe immunodeficient NOG mice after repeated superovulation with inhibin antiserum and eCG.Experimental animals · 2026Article
- Deconstructing the RAGE signaling maze: the molecular key to opening a new dimension of ovarian anti-aging.Experimental & molecular medicine · 2026Review
- Putative "ovarian awakening" in diminished ovarian reserve: a multicenter analysis demonstrates indistinguishability from regression to the mean.Journal of ovarian research · 2026Article
- Choice of laboratory insemination protocol for patients with emergency oocyte retrieval in natural cycles.BMC pregnancy and childbirth · 2025Article
- Superovulation alters telomere length and telomerase component levels in mouse oocytes.Journal of ovarian research · 2025Article
- Major depressive disorder and anti-depressant therapy markedly alters the human follicular niche DNA methylome.Reproduction (Cambridge, England) · 2025Article
- Mitochondrial Quality Control in Ovarian Function: From Mechanisms to Therapeutic Strategies.Reproductive sciences (Thousand Oaks, Calif.) · 2025Review
- Effects of multisuperovulation on the transcription and genomic methylation of oocytes and offspring.Clinical epigenetics · 2024Article
- Ameliorative Effect of Lycopene on Follicular Reserve Depletion, Oxidative Damage, Apoptosis Rate, and Hormonal Profile during Repeated Superovulations in Mice.Veterinary sciences · 2024Article
- Assessment of Repetitive Controlled Ovarian Stimulation (COS) Cycles on Oocyte Donors: Impact on Oocyte Quality and Viable Embryo Yield.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Participation of preovulatory follicles in the activation of primordial follicles in mouse ovaries.International journal of biological sciences · 2024Article
- A non-antibiotic antimicrobial drug, a biological bacteriostatic agent, is useful for treating aerobic vaginitis, bacterial vaginosis, and vulvovaginal candidiasis.Frontiers in microbiology · 2024Article
- Transcriptome profiling reveals superovulation with the gonadotropin-releasing hormone agonist trigger impaired embryo implantation in mice.Frontiers in endocrinology · 2024Article
- Maternal contributions to pregnancy success: from gamete quality to uterine environment.Animal reproduction · 2023Article
- Influence of repeated estrus synchronization treatment on hormone secretion, growth, and development of dairy goats.Frontiers in veterinary science · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For humans, ARTs (assisted reproductive technologies) have become the most effective method to treat subfertility/infertility in clinic. To obtain enough oocytes during ART, ovarian stimulation is performed by exogenous hormones, and some patients undergo several ovarian stimulation cycles. Although some adverse effects of ARTs on women and offspring are reported, few studies are focused on the effects of multiple superovulation on ovarian reserve. In the present study, we found that repeated superovulation significantly reduced primordial follicle number and the serum AMH. Compared to the decreased antral follicle number, the expression of genes related to primordial follicle activation, such as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.