Evidence map›Paper›PMID 36611783›Full record

ArticleAnimals : an open access journal from MDPI2023

Transcriptomic Study on the Lungs of Broilers with Ascites Syndrome.

Dongqing Guo, Jian Zhang, Yufeng Han, Liang Cui, Huimin Wang, Keyao Wang, Peiqi Li, Ruiqiang Deng, Jie Kang, Zhibian Duan

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Dongqing GuoCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Jian ZhangCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Yufeng HanCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Liang CuiCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Huimin WangCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Keyao WangCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Peiqi LiCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Ruiqiang DengCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Jie KangCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Zhibian DuanCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, China.
Shanxi Agricultural University · CN

Funding

the Natural Science Foundation of Shanxi Province 201901D111235
6 · The paper itself

Abstract

Although broiler ascites syndrome (AS) has been extensively studied, its pathogenesis remains unclear. The lack of cardiopulmonary function in broilers causes relative hypoxia in the body; hence, the lung is the main target organ of AS. However, the transcriptome of AS lung tissue in broilers has not been studied. In this study, an AS model was successfully constructed, and lung tissues of three AS broilers and three healthy broilers were obtained for RNA sequencing (RNA-seq) and pathological observation. The results showed that 614 genes were up-regulated and 828 genes were down-regulated in the AS group compared with the normal group. Gene Ontology (GO) functional annotation revealed the following up-regulated genes:

Indexed as

broiler ascites syndromelungmetabolic hypoxiaRNA-seq

Identifiers

PMID36611783
PMCPMC9817706
OpenAlexW4313397871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.