Evidence map›Paper›PMID 36611772›Full record

ArticleAnimals : an open access journal from MDPI2022

Evaluation of Haemostasis in Dogs Affected by Resectable Malignancy.

Barbara Bruno, Cristiana Maurella, Paola Gianella, Giulio Mengozzi, Erica Ferraris, Antonio Borrelli

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Barbara BrunoDepartment of Veterinary Science, University of Turin, Largo P. Braccini 2, 10095 Grugliasco, Italy.ORCID 0000-0003-4691-3043
Cristiana MaurellaSection of Turin, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Via Bologna 148, 10154 Turin, Italy.ORCID 0000-0003-3481-8380
Paola GianellaDepartment of Veterinary Science, University of Turin, Largo P. Braccini 2, 10095 Grugliasco, Italy.
Giulio MengozziDepartment of Public Health and Pediatric Sciences, C.so Bramante 88/90, 10100 Turin, Italy.ORCID 0000-0003-0431-8369
Erica FerrarisDepartment of Veterinary Science, University of Turin, Largo P. Braccini 2, 10095 Grugliasco, Italy.
Antonio BorrelliDepartment of Veterinary Science, University of Turin, Largo P. Braccini 2, 10095 Grugliasco, Italy.
University of Turin · ITIstituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle d'Aosta · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dogs with neoplasm are at risk of thrombosis, yet there is no information on the haemostatic alterations that may result from the surgeries performed to remove neoplastic masses. The aim of this study was to observe the characteristics of haemostasis in dogs undergoing surgery to remove a malignancy by means of rotational thromboelastometry and thrombin generation. Haemostasis was assessed immediately before surgery (T0), 24 h after surgery (T1), and two weeks after surgery (T2). Statistically significant differences were found between the thromboelastometric parameters at T0 vs. T1, with increases observed in MCF, the α angle, and G parameters in the ex-TEM and in-TEM profiles. In the thromboelastometric analysis performed after surgery differences were identified between T1 and T2, with a decrease observed in parameters such as CFT, MCF, the α angle, and G. Between T0 and T2, only a significant decrease in CT was detected in the fib-TEM profile. No differences were found in the comparison among the results obtained via thrombin generation. In dogs with resectable malignancies, the surgeries performed to remove cancer affected coagulation, causing a tendency towards hypercoagulability. The interference with coagulation was transient, and 2 weeks after surgery, the thromboelatometric results returned to those obtained before surgery (T0).

Indexed as

caninecoagulationneoplasiathrombin generationthromboelastometry

Identifiers

PMID36611772
PMCPMC9817527
OpenAlexW4313472931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.