Evidence map›Paper›PMID 36611675›Full record

ArticleAnimals : an open access journal from MDPI2022

Detection and Characterization of Feline Calicivirus Associated with Paw and Mouth Disease.

Andrea Palombieri, Vittorio Sarchese, Maria Veronica Giordano, Paola Fruci, Paolo Emidio Crisi, Giovanni Aste, Laura Bongiovanni, Valentina Rinaldi, Alessio Sposato, Michele Camero and 5 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Nanopore sequencing in veterinary medicine: from concepts to clinical applications.Frontiers in cellular and infection microbiology · 2025
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Andrea PalombieriDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0001-5903-086X
Vittorio SarcheseDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0002-2294-1624
Maria Veronica GiordanoDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.
Paola FruciDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0002-6946-8467
Paolo Emidio CrisiDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0001-5993-0059
Giovanni AsteDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.
Laura BongiovanniDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0001-8942-6048
Valentina RinaldiDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0002-5651-1358
Alessio SposatoDepartment of Veterinary Medicine, Università Aldo Moro di Bari, 70121 Bari, Italy.
Michele CameroDepartment of Veterinary Medicine, Università Aldo Moro di Bari, 70121 Bari, Italy.
Gianvito LanaveDepartment of Veterinary Medicine, Università Aldo Moro di Bari, 70121 Bari, Italy.ORCID 0000-0003-4614-677X
Vito MartellaDepartment of Veterinary Medicine, Università Aldo Moro di Bari, 70121 Bari, Italy.ORCID 0000-0002-5740-6947
Fulvio MarsilioDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0001-9552-1199
Barbara Di MartinoDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0001-6192-7166
Federica Di ProfioDepartment of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy.ORCID 0000-0002-7190-3835
University of Teramo · ITUniversity of Bari Aldo Moro · IT

Funding

Italian Ministry for Education, University and Research CUP_C46C18000530001
6 · The paper itself

Abstract

Feline calicivirus (FCV) infection in cats can led to several diverse clinical presentations, ranging from mild upper respiratory signs to virulent systemic disease. Herein, we report a paw and mouth disease case in a 7-year-old household cat due to an FCV infection. An asymptomatic cat living in the same household was also infected with FCV. Clinical and pathological investigations were combined with the molecular and phenotypical characterization of the FCV strains. The RNA of the FCV was detected using qualitative and quantitative reverse transcription (RT)-PCR assays, and FCV antigen was confirmed by immunohistochemistry. After the whole genome analysis, the strains detected in the two cats appeared to be genetically diverse from FCVs previously detected in association with paw and mouth disease and with virulent systemic disease. Interestingly, the isolates obtained in this study were resistant to low pH conditions and slightly susceptible to bile salts, but they were susceptible to a trypsin treatment, revealing a phenotype pattern that is different from that which has been observed for respiratory FCVs.

Indexed as

FCVimmunohistochemistrypaw and mouth diseasephenotypic and antigenic characterizationWGS

Identifiers

PMID36611675
PMCPMC9818015
OpenAlexW4312205574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.