Evidence map›Paper›PMID 36611664›Full record

ArticleAnimals : an open access journal from MDPI2022

Evaluating Ruminal and Small Intestinal Morphology and Microbiota Composition of Calves Fed a

Janaka Wickramasinghe, Chiron J Anderson, Can Ayhan Kaya, Patrick J Gorden, Flavio Rodrigues Borges Ribeiro, Juliane Dohms, Sydney Rigert, Stephan Schmitz-Esser, Ranga Appuhamy

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Effects of aAnimals : an open access journal from MDPI · 2025
    Article
  3. Effects ofAnimals : an open access journal from MDPI · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Janaka WickramasingheDepartment of Animal Science, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0002-9493-1513
Chiron J AndersonDepartment of Animal Science, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0002-7947-3526
Can Ayhan KayaDepartment of Livestock and Crop Production, Dicle University, 21280 Diyarbakir, Turkey.ORCID 0000-0001-8226-7603
Patrick J GordenVeterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0002-6096-0965
Flavio Rodrigues Borges RibeiroPhytobiotics, Futterzusatzstoffe GmbH, Wallufer Str. 10a, D-65343 Eltville, Germany.
Juliane DohmsPhytobiotics, Futterzusatzstoffe GmbH, Wallufer Str. 10a, D-65343 Eltville, Germany.
Sydney RigertDepartment of Animal Science, Iowa State University, Ames, IA 50011, USA.
Stephan Schmitz-EsserDepartment of Animal Science, Iowa State University, Ames, IA 50011, USA.
Ranga AppuhamyDepartment of Animal Science, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0001-8767-0303
Iowa State University · USMorphoSys (Germany) · DEDicle University · TR

Funding

Phytobiotics Futterzusatzstoffe GmbH (Eltville, Germany) ISU020627.1
6 · The paper itself

Abstract

The objective was to determine the impact of feeding MCE on ruminal and intestinal morphology and microbiota composition of calves. A total of 10 male and 10 female crossbred (dairy × beef) calves (6 d of age) were assigned randomly to control (CTL; n = 10) or MCE-supplemented (TRT; n = 10) groups. The MCE was fed in the milk replacer and top-dressed on the calf starter during pre-weaning (6 to 49 d) and post-weaning (50 to 95 d) periods, respectively. Calves were slaughtered at 95 d to collect rumen and intestinal samples to determine volatile fatty acid (VFA) profile, mucosal morphology, and microbiota composition. The effects of MCE were analyzed by accounting for the sex and breed effects. Feeding MCE increased rumen papillae length (p = 0.010) and intestinal villus height: crypt depth (p < 0.030) compared to CTL but did not affect rumen VFA profile. The TRT had a negligible impact on microbial community composition in both the rumen and the jejunum. In conclusion, feeding MCE from birth through weaning can improve ruminal and small intestinal mucosa development of calves despite the negligible microbiota composition changes observed post-weaning.

Indexed as

crossbred calvespapillae lengthphytogenic feed additivesmall intestinevillus height

Identifiers

PMID36611664
PMCPMC9817497
OpenAlexW4312173631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.