Evidence map›Paper›PMID 36611322›Full record

ArticleDiagnostics (Basel, Switzerland)2022

In Vivo Evaluation of the Effects of SMILE with Different Amounts of Stromal Ablation on Corneal Biomechanics by Optical Coherence Elastography.

Yirui Zhu, Yanzhi Zhao, Yubao Zhang, Hongwei Yang, Jiulin Shi, Hongling Cai, Dong Zhang, Guofu Huang, Xingdao He, Xiaoshan Wu

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  6. CCL18, CHI3L1, ANG2, IL-6 systemic levels are associated with the extent of lung damage and radiomic features in SARS-CoV-2 infection.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yirui ZhuSchool of Physics, Nanjing University, Nanjing 210093, China.ORCID 0000-0002-8722-6234
Yanzhi ZhaoSchool of Medical, Nanchang University, Nanchang 330031, China.
Yubao ZhangSchool of Testing and Optoelectronic Engineering, Nanchang Hangkong University, Nanchang 330063, China.
Hongwei YangSchool of Medical, Nanchang University, Nanchang 330031, China.
Jiulin ShiSchool of Testing and Optoelectronic Engineering, Nanchang Hangkong University, Nanchang 330063, China.
Hongling CaiSchool of Physics, Nanjing University, Nanjing 210093, China.
Dong ZhangSchool of Physics, Nanjing University, Nanjing 210093, China.ORCID 0000-0001-5297-8658
Guofu HuangSchool of Medical, Nanchang University, Nanchang 330031, China.
Xingdao HeSchool of Testing and Optoelectronic Engineering, Nanchang Hangkong University, Nanchang 330063, China.
Xiaoshan WuSchool of Physics, Nanjing University, Nanjing 210093, China.
Nanjing University · CNNanchang Hangkong University · CNNanchang University · CN

Funding

Ministry of Science and Technology of the People's Republic of China 2018YFE0115700National Natural Science Foundation of China 12164028National Natural Science Foundation of China 41576033National Natural Science Foundation of China 51863016National Natural Science Foundation of China 61177096National Natural Science Foundation of China 61865013
6 · The paper itself

Abstract

This work aims to depth-resolved quantitatively analyze the effect of different stromal ablation amounts on the corneal biomechanical properties during small incision lenticule extraction (SMILE) using optical coherence elastography (OCE). A 4.5-MHz ultrasonic transducer was used to excite elastic waves in the corneal tissue. The OCE system combined with the antisymmetric Lamb wave model was employed to achieve a high-resolution, high-sensitivity, and depth-resolved quantitative detection of the corneal Young's modulus. Eighteen rabbits were randomly divided into three groups; each group had six rabbits. The first and second groups underwent -3D and -6D SMILE surgeries, and the third group was the control group, respectively. Young's modulus of the corneal cap and residual stromal bed (RSB) were both increased after SMILE, which shared the stress under intraocular pressure (IOP). Furthermore, the Young's modulus of both the corneal cap and RSB after 3D SMILE group were significantly lower than that in the -6D group, which indicated that the increases in the post-operative corneal Young's modulus were positively correlated with the amount of stromal ablation. The OCE system for quantitative spatial characterization of corneal biomechanical properties can provide useful information on the extent of safe ablation for SMILE procedures.

Indexed as

biomechanical properties of cornealcorneal refractive surgeryoptical coherence elastographyoptical coherence tomographysmall incision lenticule extraction

Identifiers

PMID36611322
PMCPMC9818797
OpenAlexW4312173712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.