Evidence map›Paper›PMID 36610707›Full record

ArticleBioinformatics (Oxford, England)2023

SIMBSIG: similarity search and clustering for biobank-scale data.

Michael F Adamer, Eljas Roellin, Lucie Bourguignon, Karsten Borgwardt

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael F AdamerDepartment of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.ORCID 0000-0002-8996-7167
Eljas RoellinDepartment of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.
Lucie BourguignonDepartment of Health Sciences and Technology, ETH Zurich, 8008 Zurich, Switzerland.
Karsten BorgwardtDepartment of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.ORCID 0000-0001-7221-2393

Funding

Swiss National Science Foundation PZ00P3_186101
6 · The paper itself

Abstract

summaryIn many modern bioinformatics applications, such as statistical genetics, or single-cell analysis, one frequently encounters datasets which are orders of magnitude too large for conventional in-memory analysis. To tackle this challenge, we introduce SIMBSIG (SIMmilarity Batched Search Integrated GPU), a highly scalable Python package which provides a scikit-learn-like interface for out-of-core, GPU-enabled similarity searches, principal component analysis and clustering. Due to the PyTorch backend, it is highly modular and particularly tailored to many data types with a particular focus on biobank data analysis. AVAILABILITY AND IMPLEMENTATION: SIMBSIG is freely available from PyPI and its source code and documentation can be found on GitHub (https://github.com/BorgwardtLab/simbsig) under a BSD-3 license.

Indexed as

Biological Specimen BanksSoftwareCluster AnalysisComputational BiologyDocumentation

Identifiers

PMID36610707
PMCPMC9825260

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.