Evidence map›Paper›PMID 36610555›Full record

ArticleInternational journal for parasitology2023

Use the force, fluke: Ligand-independent gating of Schistosoma mansoni ion channel TRPM

Evgeny G Chulkov, Elena Isaeva, Cheryl L Stucky, Jonathan S Marchant

Open access · greenAbstract read
In one paragraph

Article in International journal for parasitology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. TRPtracker: a community database for monitoring praziquantel sensitivity at TRPMInternational journal for parasitology. Drugs and drug resistance · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Praziquantel activates a native cation current inFrontiers in parasitology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Evgeny G ChulkovDepartment of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee WI 53226, USA.
Elena IsaevaDepartment of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee WI 53226, USA.
Cheryl L StuckyDepartment of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee WI 53226, USA.
Jonathan S MarchantDepartment of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee WI 53226, USA. Electronic address: JMarchant@mcw.edu.
Medical College of Wisconsin · US

Funding

FUNCTIONAL ANALYSIS OF DISTINCT NOCICEPTOR POPULATIONSR01NS040538 · NINDS · MEDICAL COLLEGE OF WISCONSIN · PI STUCKY, CHERYL LOUISE · 2000 to 2019
$6.2M
Pain Mechanisms in Fabry DiseaseR37NS108278 · NINDS · MEDICAL COLLEGE OF WISCONSIN · PI STUCKY, CHERYL LOUISE · 2019 to 2025
$5.6M
Resolving the properties of schistosome TRPMPZQ, the target of the anthelmintic drug praziquantelR01AI145871 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI Wei Liu, JONATHAN S MARCHANT · 2020 to 2026
$3.1M
NIAID NIH HHS R01 AI145871NINDS NIH HHS R01 NS040538NINDS NIH HHS R37 NS108278
6 · The paper itself

Abstract

The parasitic flatworm ion channel, TRPM

Indexed as

Helminth ProteinsSchistosoma mansoniTRPM Cation ChannelsAdenosine Diphosphate RiboseAnimalsHumansPressureAdenosine Diphosphate RiboseHelminth ProteinsTRPM Cation ChannelsAnthelminticElectrophysiologyIon channelMechanosensitivityParasite

Identifiers

PMID36610555
PMCPMC10258140
OpenAlexW4313593765

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.