Evidence map›Paper›PMID 36609861›Full record

Trial reportThe International journal of eating disorders2023

A pilot randomized controlled trial of a cognitive-behavioral therapy guided self-help mobile app for the post-acute treatment of anorexia nervosa: A registered report.

Ellen E Fitzsimmons-Craft, Agatha A Laboe, Claire McGinnis, Marie-Laure Firebaugh, Jillian Shah, Michael Wallendorf, Corinna Jacobi, Anna M Bardone-Cone, Kathleen M Pike, C Barr Taylor and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of eating disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ellen E Fitzsimmons-CraftDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0001-7064-3835
Agatha A LaboeDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.
Claire McGinnisDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.
Marie-Laure FirebaughDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.
Jillian ShahDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0001-6006-3263
Michael WallendorfDivision of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA.
Corinna JacobiDepartment of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.
Anna M Bardone-ConeDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-1855-6328
Kathleen M PikeDepartment of Psychiatry, Columbia University, New York, New York, USA.ORCID 0000-0003-4584-4250
C Barr TaylorDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-4564-6548
Denise E WilfleyDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Brian N Finck · 1999 to 2026
$30.2M
Harnessing Mobile Technology to Reduce Mental Health Disorders in College PopulationsR01MH115128 · NIMH · WASHINGTON UNIVERSITY · PI EISENBERG, DANIEL, NEWMAN, MICHELLE G · 2018 to 2022
$4.1M
Developing an Optimized Conversational Agent or "Chatbot" to Facilitate Mental Health Services Use in Individuals with Eating DisordersK08MH120341 · NIMH · WASHINGTON UNIVERSITY · PI FITZSIMMONS-CRAFT, ELLEN E. · 2019 to 2023
$824k
Development and Pilot Testing of a Cognitive-Behavioral Therapy-Guided Self-Help Mobile App for the Post-Acute Treatment of Anorexia NervosaR34MH127203 · NIMH · WASHINGTON UNIVERSITY · PI FITZSIMMONS-CRAFT, ELLEN E. · 2021 to 2023
$730k
NIDDK NIH HHS P30 DK056341NIMH NIH HHS K08 MH120341NIMH NIH HHS R01 MH115128NIMH NIH HHS R34 MH127203
6 · The paper itself

Abstract

introductionRelapse following acute treatment for anorexia nervosa (AN) is common. Evidence suggests cognitive-behavioral therapy (CBT) may be useful in the post-acute period, but few patients have access to trained providers. mHealth technologies have potential to increase access to high-quality care for AN, including in the post-acute period. The aim of this study is to estimate the preliminary feasibility and effectiveness of a CBT-based mobile intervention plus treatment as usual (TAU), offered with and without an accompanying social networking feature.

methodIn the current pilot randomized controlled trial, women with AN who have been discharged from acute treatment in the past 2 months (N = 90) will be randomly assigned to a CBT-based mobile intervention plus treatment as usual (TAU), a CBT-based mobile intervention including social networking plus TAU, or TAU alone. We will examine feasibility, acceptability, and preliminary effectiveness of the three conditions in terms of reducing eating disorder psychopathology, reducing frequency of eating disorder behaviors, achieving weight maintenance, reducing depression and suicidal ideation, and reducing clinical impairment. We will examine rehospitalization and full recovery rates in an exploratory fashion. We will also examine whether the mobile intervention and social networking feature change the proposed targets and whether changes in targets are associated with benefit, as well as conduct exploratory analyses to identify within-mobile intervention predictors and moderators of outcome. DISCUSSION: Ultimately, this research may lead to increased access to evidence-based treatment for individuals with AN and prevention of the extreme negative consequences that can result from this serious disorder. PUBLIC SIGNIFICANCE: Relapse after acute treatment for anorexia nervosa is common, and few patients have access to trained providers to support them following acute care. This study will pilot a coached mobile app, including a social networking component, for this population. If ultimately successful, our approach could greatly increase access to evidence-based treatment for individuals with anorexia nervosa and ultimately prevent the extreme negative consequences that can result from this serious disorder.

Indexed as

Anorexia NervosaCognitive Behavioral TherapyMobile ApplicationsFemaleHumansPilot ProjectsRecurrenceTreatment Outcomeanorexia nervosaeating disordersmobile interventionpost-acute treatmentsocial networking

Identifiers

PMID36609861
PMCPMC10019771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.