Evidence map›Paper›PMID 36609350›Full record

ArticleBritish journal of sports medicine2023

Associations of cardiorespiratory fitness and body mass index with incident restrictive spirometry pattern.

Joey M Saavedra, Angelique G Brellenthin, Bong Kil Song, Duck-Chul Lee, Xuemei Sui, Steven N Blair

Abstract read
In one paragraph

Article in British journal of sports medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Joey M SaavedraDepartment of Kinesiology, Iowa State University, Ames, Iowa, USA.ORCID http://orcid.org/0000-0002-6360-9433
Angelique G BrellenthinDepartment of Kinesiology, Iowa State University, Ames, Iowa, USA abrellen@iastate.edu.ORCID http://orcid.org/0000-0003-2038-389X
Bong Kil SongDepartment of Kinesiology, Iowa State University, Ames, Iowa, USA.
Duck-Chul LeeDepartment of Kinesiology, Iowa State University, Ames, Iowa, USA.ORCID http://orcid.org/0000-0001-6423-5341
Xuemei SuiDepartment of Exercise Science, University of South Carolina, Columbia, South Carolina, USA.
Steven N BlairDepartments of Exercise Science and Epidemiology & Biostatistics, University of South Carolina, Columbia, South Carolina, USA.

Funding

Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise (Cardio-RACE)R01HL133069 · NHLBI · IOWA STATE UNIVERSITY · PI LEE, DUCK-CHUL · 2016 to 2020
$3.4M
Impact of Physical Fitness and Exercise on HealthR37AG006945 · NIA · COOPER INSTITUTE · PI BLAIR, STEVEN N. · 2002 to 2005
$2.7M
CORONARY ARTERY CALCIUM, EXERCISE TESTS, AND CHD OUTCOMER01HL062508 · NHLBI · COOPER INSTITUTE · PI LAMONTE, MICHAEL J · 1999 to 2004
$2.5M
IMPACT OF PHYSICAL FITNESS &EXERCISE ON HEALTHR01AG006945 · NIA · COOPER INSTITUTE · PI BLAIR, STEVEN N. · 1986 to 2001
$1.1M
Understanding Patterns of Change in Obesity and Physical Activity in AdultsR21DK088195 · NIDDK · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI SUI, XUEMEI · 2010 to 2011
$397k
NHLBI NIH HHS R01 HL062508NHLBI NIH HHS R01 HL133069NIA NIH HHS R01 AG006945NIA NIH HHS R37 AG006945NIDDK NIH HHS R21 DK088195
6 · The paper itself

Abstract

objectivesRestrictive spirometry pattern (RSP) suggests an impairment of lung function associated with a significantly increased risk of premature mortality. We evaluated the independent and joint associations of cardiorespiratory fitness (CRF) and body mass index with incident RSP.

methodsData from the Aerobics Centre Longitudinal Study included 12 360 participants (18-82 years). CRF was assessed by maximal treadmill test and categorised into five groups. Body mass index was categorised into normal weight (<25.0 kg/m

resultsThere were 900 (7.3%) cases of RSP (mean follow-up: 6.9 years). Compared with category 1 ('least fit'), HRs (95% CIs) of RSP were 0.78 (0.63 to 0.96), 0.68 (0.54 to 0.86), 0.70 (0.55 to 0.88) and 0.59 (0.45 to 0.77) in categories 2, 3, 4 and 5 (most fit), respectively, after adjusting for confounders including body mass index. Compared with normal weight, HRs (95% CIs) of RSP were 1.06 (0.91 to 1.23) and 1.30 (1.03 to 1.64) in overweight and obese, respectively. However, the association between obesity and RSP was attenuated when additionally adjusting for CRF (HR 1.08, 95% CI 0.84 to 1.39). Compared with the 'unfit and overweight/obese' group, HRs (95% CIs) for RSP were 1.35 (0.98 to 1.85), 0.77 (0.63 to 0.96) and 0.70 (0.56 to 0.87) in the 'unfit and normal weight,' 'fit and overweight/obese' and 'fit and normal weight' groups, respectively.

conclusionsLow CRF was associated with a greater incidence of RSP, irrespective of body mass index. Future studies are needed to explore potential underlying mechanisms of this association and to prospectively evaluate if improving CRF reduces the risk of developing RSP.

Indexed as

Cardiorespiratory FitnessBody Mass IndexHumansLongitudinal StudiesObesityOverweightPhysical FitnessRisk FactorsSpirometryBody Mass IndexLungPhysical fitness

Identifiers

PMID36609350
PMCPMC10323034

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.