Evidence map›Paper›PMID 36609330›Full record

Observational studyBMJ open2023

Leveraging the South African Diabetes Prevention Programme to screen for chronic kidney disease: an observational study.

Cindy George, Jillian Hill, Unati Nqebelele, Nasheeta Peer, A P Kengne

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cindy GeorgeNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa cindy.george@mrc.ac.za.ORCID 0000-0002-4561-0529
Jillian HillNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
Unati NqebeleleNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
Nasheeta PeerNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
A P KengneNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the viability of leveraging an existing screening programme (the South African Diabetes Prevention Programme (SA-DPP)) to screen for chronic kidney disease (CKD), by assessing the yield of CKD cases among those participating in the programme.

designObservational study conducted between 2017 and 2019.

setting16 resource-poor communities in Cape Town, South Africa.

participants690 participants, aged between 25 and 65 years, identified as at high risk for type 2 diabetes mellitus (T2DM) by the African Diabetes Risk Score. PRIMARY OUTCOME MEASURE: The prevalence of CKD among those participating in the SA-DPP.

resultsOf the 2173 individuals screened in the community, 690 participants underwent further testing. Of these participants, 9.6% (n=66) and 18.1% (n=125) had screen-detected T2DM and CKD (defined as an estimated glomerular filtration rate (eGFR) of<60 mL/min/1.73 m

conclusionThe fact that almost one in five participants identified as high risk for T2DM had CKD underscores the value of including markers of kidney function in an existing screening programme. By using an opportunistic approach to screen high-risk individuals, those with CKD can be identified and appropriately treated to reduce disease progression.

Indexed as

Diabetes Mellitus, Type 2Renal Insufficiency, ChronicAdultAgedCreatinineGlomerular Filtration RateHumansMiddle AgedRisk FactorsSouth AfricaCreatinineepidemiologynephrologypublic health

Identifiers

PMID36609330
PMCPMC9827250

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.