Evidence map›Paper›PMID 36609244›Full record

SynthesisBMC anesthesiology2023

Analgesic effect of erector spinae plane block in adults undergoing laparoscopic cholecystectomy: a systematic review and meta-analysis of randomized controlled trials.

Xiaoli Yang, Yu Zhang, Yong Chen, Mingxing Xu, Xue Lei, Qiang Fu

2 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC anesthesiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07187310 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Analgesic Efficacy of EXORA Block Versus Erector Spinae Plane Block in Patients Undergoing Laparoscopic Cholecystectomy Under General Anesthesia

TypeinterventionalSponsorFayoum University HospitalRan2025 to 2026Enrolled114ConditionsPostoperative PainArmsEXORA block, Erector Spinae Plane block
NCT07556536 narecruitingnot on this mapstarted 2026, after this paper: background citation

Analgesic Efficacy of Ultrasound-Guided Serratus Intercostal Plane Block Versus Erector Spinae Plane Block for Postoperative Pain Control After Open Nephrectomy: A Prospective Randomized Controlled Trial

TypeinterventionalSponsorFayoum University HospitalRan2026 to 2027Enrolled132ConditionsPost Operative Pain, Open NephrectomyArmsSerratus Intercostal Plane Block, Erector Spinae Plane Block
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  17. Postoperative analgesic efficacy of M-TAPA.Journal of anesthesia · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaoli YangDepartment of Anesthesiology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.
Yu ZhangDepartment of Anesthesiology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.
Yong ChenDepartment of Anesthesiology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.
Mingxing XuDepartment of Anesthesiology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.
Xue LeiDepartment of Anesthesiology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.
Qiang FuDepartment of Anesthesiology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China. fuqiang1878@outlook.com.
Chengdu Third People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic cholecystectomy is the gold standard surgical procedure for treating gallstone disease. Despite it being minimally invasive, various medications and methods are used to alleviate postoperative pain, and some patients still experience moderate-to-severe pain. This is a crucial problem that must be solved to avoid chronic pain. As part of postoperative multimodal analgesia, regional block is being increasingly applied in surgery under ultrasound guidance. We aimed to evaluate the analgesic effect of erector spinae plane block in adult patients undergoing laparoscopic cholecystectomy.

methodsPubMed, Cochrane Library, EMBASE, and Web of Science were searched for randomized controlled trials investigating the efficacy of erector spinae plane block on postoperative pain after laparoscopic cholecystectomy. The primary outcome was the postoperative pain score. The secondary outcomes were the cumulative intraoperative and postoperative opioid consumption at 24 h, incidence of postoperative nausea and vomiting, and shoulder pain after surgery. The results were pooled using the fixed- or random-effects model with Review Manager 5.3.

resultsFifteen randomized controlled trials involving 947 patients were included in the analysis. Postoperative pain score in the erector spinae plane block group was lower than that in the control group at postoperative 12 h (MD - 0.81, 95% CI - 1.1 to - 0.51, p < 0.00001) and 24 h (MD - 0.41, 95% CI - 0.62 to - 0.19, p = 0.0002). Cumulative opioid consumption was lower in the erector spinae plane block group than in the control group at postoperative 24 h (MD - 7.88, 95% CI - 10.17 to - 5.58, p < 0.00001). The erector spinae plane block group also experienced a lower incidence of postoperative nausea and vomiting than the control group. Opioid consumption and the incidence of postoperative nausea and vomiting were similar between the erector spinae plane block group and other block groups, including the oblique subcostal transversus abdominis plane block and quadratus lumborum block groups.

conclusionsUltrasound-guided erector spinae plane block provides effective postoperative analgesia in adults undergoing laparoscopic cholecystectomy.

Indexed as

Cholecystectomy, LaparoscopicNerve BlockAdultAnalgesics, OpioidHumansPain MeasurementPostoperative Nausea and VomitingPostoperative PainRandomized Controlled Trials as TopicUltrasonography, InterventionalAnalgesics, OpioidAdultErector spinae plane blockMeta-analysisPostoperative pain

Identifiers

PMID36609244
PMCPMC9817294
OpenAlexW4313648405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.