Evidence map›Paper›PMID 36608980›Full record

ArticleBehavior therapy2023

Cognitive and Behavioral Contributions to Depression Severity, Quality of Life, and Functioning Among People Living With HIV in South Africa.

Lena S Andersen, Amelia M Stanton, Jessica F Magidson, John A Joska, Conall O'Cleirigh, Jasper S Lee, Ashraf Kagee, Jade A Witten, Steven A Safren

Open access · hybridAbstract read
In one paragraph

Article in Behavior therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 4 countries.

Lena S AndersenUniversity of Copenhagen. Electronic address: lena.andersen@sund.ku.dk.
Amelia M StantonMassachusetts General Hospital and Harvard Medical School.
Jessica F MagidsonUniversity of Maryland.
John A JoskaUniversity of Copenhagen.
Conall O'CleirighMassachusetts General Hospital and Harvard Medical School.
Jasper S LeeUniversity of Miami.
Ashraf KageeStellenbosch University.
Jade A WittenBangor University.
Steven A SafrenUniversity of Miami.
University of Copenhagen · DKUniversity of Miami · USBangor University · GBHarvard University · USMassachusetts General Hospital · USStellenbosch University · ZAUniversity of Maryland, College Park · US

Funding

University of Miami Developmental HIV/AIDS Mental Health Research Center (D-ARC)P30MH116867 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2019 to 2023
$6.5M
Nurse-Delivered CBT for Depression-Adherence in HIV Primary Care S. AfricaR01MH103770 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI O'CLEIRIGH, CONALL MICHAEL, SAFREN, STEVEN A · 2015 to 2019
$3.1M
Boston University Medical Campus-Massachusetts General Hospital Global Psychiatric Clinical Research Training ProgramT32MH116140 · NIMH · BOSTON MEDICAL CENTER · PI FRICCHIONE, GREGORY L, HENDERSON, DAVID C · 2018 to 2022
$1.6M
Hybrid Effectiveness-Implementation Trial for ART Adherence and Substance Use in HIV Care in South AfricaK23DA041901 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI MAGIDSON, JESSICA F · 2016 to 2020
$1.0M
Reducing psychological barriers to PrEP persistence among pregnant and postpartum women in Cape Town, South AfricaK23MH131438 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Amelia M. Stanton · 2022 to 2026
$933k
Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
Patient-Oriented Substance Use/Smoking Cessation Research in HIV Treatment and PreventionK24DA062568 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Conall Michael O'Cleirigh · 2024 to 2026
$639k
Effects of Syndemics on HIV Outcomes in South AfricaF31MH122279 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI LEE, JASPER SAMUEL · 2020 to 2020
$41k
NIDA NIH HHS K23 DA041901NIDA NIH HHS K24 DA040489NIDA NIH HHS K24 DA062568NIMH NIH HHS F31 MH122279NIMH NIH HHS K23 MH131438NIMH NIH HHS P30 MH116867NIMH NIH HHS R01 MH103770NIMH NIH HHS T32 MH116140
6 · The paper itself

Abstract

Cognitive-behavioral treatments for depression typically address both behavioral (e.g., activation) and cognitive (e.g., rumination) components, and consequently improve quality of life (QOL) and function in high-resource settings. However, little is known about the cross-cultural applicability and relative contribution of these components to depression symptom severity, QOL, and functional impairment in South Africa and other resource-limited global settings with high HIV prevalence rates. Persons with HIV (N = 274) from a peri-urban community outside Cape Town, South Africa, were administered multiple measures of depression (Hamilton Depression Scale, Centre for Epidemiological Studies Depression Scale, South African Depression Scale), cognitive and behavioral components related to depression (Ruminative Response Scale, Behavioral Activation for Depression Scale), and measures of QOL and functioning (Sheehan Disability Scale, Quality of Life Enjoyment and Satisfaction Scale-Short Form). Multiple linear regression models were fit to assess the relative contribution of behavioral and cognitive components to depression severity, QOL, and functional impairment in this population. Models accounting for age and sex revealed that lower levels of behavioral activation (BA) were significantly associated with all measures of depression, as well as with QOL and functional impairment (all ps < .01). Rumination was associated with all measures of depression (all ps < .01), but not with QOL or functional impairment. The consistent and unique association of BA with depression, QOL, and functional impairment bolsters its importance as a treatment target for this population.

Indexed as

HIV InfectionsQuality of LifeCognitionDepressionHumansSouth Africabehavioral activationdepressionHIVruminationSouth Africa

Identifiers

PMID36608980
PMCPMC13266153
OpenAlexW4285601656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.