Evidence map›Paper›PMID 36608574›Full record

ReviewCurrent opinion in microbiology2023

Within-host evolution of the gut microbiome.

Tanja Dapa, Daniel Pgh Wong, Kimberly S Vasquez, Karina B Xavier, Kerwyn Casey Huang, Benjamin H Good

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Genomic-microbial coevolution in human development: chromosome 2 fusion, and human accelerated regions.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Analysis of metagenomic data.Nature reviews. Methods primers · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tanja DapaInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Daniel Pgh WongDepartment of Applied Physics, Stanford University, Stanford, CA 94305, USA.
Kimberly S VasquezDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Karina B XavierInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal. Electronic address: kxavier@igc.gulbenkian.pt.
Kerwyn Casey HuangDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: kchuang@stanford.edu.
Benjamin H GoodDepartment of Applied Physics, Stanford University, Stanford, CA 94305, USA. Electronic address: bhgood@stanford.edu.

Funding

A universal pipeline for functional characterization of the human microbiota at a massive scaleRM1GM135102 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BUIE, CULLEN RICHARD, DEUTSCHBAUER, ADAM M · 2020 to 2024
$7.6M
Quantitative approaches for mapping the real-time evolution of the gut microbiotaR35GM146949 · NIGMS · STANFORD UNIVERSITY · PI Benjamin H Good · 2022 to 2026
$2.0M
NIGMS NIH HHS R35 GM146949NIGMS NIH HHS RM1 GM135102
6 · The paper itself

Abstract

Gut bacteria inhabit a complex environment that is shaped by interactions with their host and the other members of the community. While these ecological interactions have evolved over millions of years, mounting evidence suggests that gut commensals can evolve on much shorter timescales as well, by acquiring new mutations within individual hosts. In this review, we highlight recent progress in understanding the causes and consequences of short-term evolution in the mammalian gut, from experimental evolution in murine hosts to longitudinal tracking of human cohorts. We also discuss new opportunities for future progress by expanding the repertoire of focal species, hosts, and surrounding communities, and by combining deep-sequencing technologies with quantitative frameworks from population genetics.

Indexed as

Gastrointestinal MicrobiomeAnimalsBacteriaHumansMammalsMice

Identifiers

PMID36608574
PMCPMC9993085

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.