ArticleJournal of psychosomatic research2023
Symptoms that remain after depression treatment in patients with coronary heart disease.
Article in Journal of psychosomatic research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Do complex psychometric analyses really matter? Comparing multiple approaches using individual participant data from antidepressant trials.Psychological medicine · 2025Article
- Intelligent Bi-LSTM with Architecture Optimization for Heart Disease Prediction in WBAN through Optimal Channel Selection and Feature Selection.Biomedicines · 2023Article
- Cardiovascular disease and depression: a narrative review.Frontiers in cardiovascular medicine · 2023Review
- New Perspectives on Treatment of Depression in Coronary Heart Disease.Psychosomatic medicineArticle
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Authors and funding
4 authors.
Funding
Abstract
objectiveSymptoms which commonly remain after treatment for major depression increase the risk of relapse and recurrence in medically well patients. The same symptoms predict major adverse cardiac events in observational studies of patients with coronary heart disease (CHD). The purpose of this study was to determine the prevalence and predictors of residual depression symptoms in depressed patients with CHD-.
methodsBeck Depression Inventory-II data from two randomized clinical trials and an uncontrolled treatment study of depression in patients with CHD were combined to determine the prevalence and predictors of residual symptoms.
resultsLoss of energy, loss of pleasure, loss of interest, fatigue, and difficulty concentrating were the five most common residual symptoms in all three studies. They are also among the most common residual symptoms in medically well patients who are treated for depression. The severity of pre-treatment anxiety predicted the post-treatment persistence of all these symptoms except for loss of energy.
conclusionsThe most common post-treatment residual symptoms found in this study of patients with coronary heart disease and comorbid major depression are the same as those that have been reported in previous studies of medically-well depressed patients. This suggests that they may be resistant to standard depression treatments across diverse patient populations. More effective treatments for these symptoms are needed.
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