Evidence map›Paper›PMID 36608338›Full record

ArticleACS sensors2023

Mechanosensitive Channel-Based Optical Membrane Tension Reporter.

Yen-Yu Hsu, Agnes M Resto Irizarry, Jianping Fu, Allen P Liu

Open access · greenAbstract read
In one paragraph

Article in ACS sensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Tension TRAAKer: a chemigenetic fluorescent membrane tension reporter.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yen-Yu HsuDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.
Agnes M Resto IrizarryDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.
Jianping FuDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.ORCID 0000-0001-9629-6739
Allen P LiuDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.ORCID 0000-0002-0309-7018
University of Michigan · US

Funding

Development of a mechanosensitive synthetic cell for mediating intercellular communication - Diversity SupplementR01EB030031 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, ALLEN PO-CHIH · 2020 to 2024
$1.3M
Repurposing Bacterial Mechanosensitive Channel as a Membrane Tension Biosensor - Diversity SupplementR21GM134157 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, ALLEN PO-CHIH · 2019 to 2020
$521k
The Goldman Chip: A bioMEMS Platform for Integrating Patch Clamp with Ion-SelectiR21GM103467 · NIGMS · PURDUE UNIVERSITY · PI RICKUS, JENNA L · 2012 to 2012
$184k
NIBIB NIH HHS R01 EB030031NIGMS NIH HHS R21 GM103467NIGMS NIH HHS R21 GM134157
6 · The paper itself

Abstract

Plasma membrane tension functions as a global physical organizer of cellular activities. Technical limitations of current membrane tension measurement techniques have hampered in-depth investigation of cellular membrane biophysics and the role of plasma membrane tension in regulating cellular processes. Here, we develop an optical membrane tension reporter by repurposing an

Indexed as

Escherichia coli ProteinsIon ChannelsCell MembraneEscherichia coliEscherichia coli ProteinsIon Channelscell mechanicsmechanosensitive channelmembrane tensionprotein engineeringreporter

Identifiers

PMID36608338
PMCPMC10028359
OpenAlexW4313612148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.