Evidence map›Paper›PMID 36608128›Full record

ArticleScience advances2023

CD47 halts

Lalita Mazgaeen, Matthew Yorek, Saurabh Saini, Peter Vogel, David K Meyerholz, Thirumala-Devi Kanneganti, Prajwal Gurung

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Effects ofCurrent issues in molecular biology · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lalita MazgaeenInflammation Program, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0001-9467-3705
Matthew YorekInflammation Program, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-4737-9367
Saurabh SainiInflammation Program, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0001-8312-3521
Peter VogelAnimal Resources Center and the Veterinary Pathology Core, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-7535-0545
David K MeyerholzDepartment of Pathology, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0003-1552-3253
Thirumala-Devi KannegantiDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-6395-6443
Prajwal GurungInflammation Program, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-7451-9433
University of Iowa · USSt. Jude Children's Research Hospital · US

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Amy Leanne Ryan · 1998 to 2026
$30.5M
Implicating a previously unknown Dectin1-RIPK2-CARD9 signaling in providing resistance against Leishmania major infectionR01AI155425 · NIAID · UNIVERSITY OF IOWA · PI GURUNG, PRAJWAL · 2021 to 2025
$2.5M
Elucidating CD47-SHP1 biology to understand autoinflammatory disordersR21AI148904 · NIAID · UNIVERSITY OF IOWA · PI GURUNG, PRAJWAL · 2020 to 2021
$386k
Elucidating cellular and molecular mechanisms regulating SHP1-mediated inflammatory skin diseaseK22AI127836 · NIAID · UNIVERSITY OF IOWA · PI GURUNG, PRAJWAL · 2018 to 2019
$269k
NIAID NIH HHS K22 AI127836NIAID NIH HHS R01 AI155425NIAID NIH HHS R21 AI148904NIDDK NIH HHS P30 DK054759
6 · The paper itself

Abstract

Mice with SHP1 proteins, which have a single amino acid substitution from tyrosine-208 residue to asparagine (hereafter

Indexed as

CD47 AntigenNeutrophilsAnimalsInflammationMiceProtein Tyrosine Phosphatase, Non-Receptor Type 6CD47 AntigenProtein Tyrosine Phosphatase, Non-Receptor Type 6PTPN6 protein, human

Identifiers

PMID36608128
PMCPMC9821860
OpenAlexW4313706761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.