Evidence map›Paper›PMID 36607169›Full record

ArticleThe neuroradiology journal2023

Factors related to white thrombi in acute ischemic stroke in cancer patients.

Hiroyuki Ikeda, Ryota Ishibashi, Masanori Kinosada, Minami Uezato, Hidenobu Hata, Ryosuke Kaneko, Tomoko Hayashi, Haruki Yamashita, Ryotaro Nukata, Kensuke Takada and 3 more

Open access · greenAbstract read
In one paragraph

Article in The neuroradiology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Impact of D-dimer on the outcomes of endovascular thrombectomy for acute ischemic stroke: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Hiroyuki IkedaDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.ORCID 0000-0001-5710-7456
Ryota IshibashiDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.ORCID 0000-0002-1646-9044
Masanori KinosadaDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.
Minami UezatoDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.
Hidenobu HataDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.
Ryosuke KanekoDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.ORCID 0000-0002-6864-5628
Tomoko HayashiDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.
Haruki YamashitaDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.
Ryotaro NukataDepartment of Neurology, Kurashiki Central Hospital, Kurashiki, Japan.
Kensuke TakadaDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.
Yoshitaka KurosakiDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.ORCID 0000-0003-0738-760X
Masaki ChinDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.
Sen YamagataDepartment of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.
Kurashiki Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThrombi in cerebral large vessel occlusion associated with active cancer are often fibrin and platelet-rich white thrombi. However, evaluating the thrombus composition in a short time before thrombectomy is often ineffective. We sought to determine factors related to white thrombi in acute ischemic stroke due to large vessel occlusion in cancer patients.

methodsConsecutive cancer patients undergoing thrombectomy for acute ischemic stroke due to large vessel occlusion between January 2018 and May 2022 were retrospectively reviewed. The patients were classified into white thrombus and red thrombus groups on the basis of the pathological findings of retrieved thrombi. Patient characteristics and laboratory findings were compared between the two groups.

resultsThere were 12 patients in the white thrombus group and 11 patients in the red thrombus group. Active cancer was significantly more in the white thrombus group than in the red thrombus group (91.7% vs. 36.3%,

conclusionsIn acute ischemic stroke in cancer patients, active cancer, no internal carotid artery occlusion, and higher D-dimer levels (≥3.5 μg/mL) may be associated with occlusion with fibrin and platelet-rich white thrombi.

Indexed as

Arterial Occlusive DiseasesBrain IschemiaIschemic StrokeNeoplasmsStrokeThrombosisFibrinHumansRetrospective StudiesThrombectomyFibrinCancerischemic strokethrombectomywhite thrombus

Identifiers

PMID36607169
PMCPMC10588610
OpenAlexW4313645467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.