ReviewBMJ open2022
Towards definitions of critical illness and critical care using concept analysis.
Review in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 73 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The African Critical Illness Outcomes Study
Evaluation of Ovarian Reserve in Critically Ill Patients Followed in the Intensive Care Unit
Who cites it
73 citing papers in PubMed, 4 syntheses or guidelines pooled it, 160 citations in OpenAlex.
- Critical care delivery models in emergency departments: a systematic review of the literature and meta-analysis of related outcome effects.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Pooled it
- Review article: Use of prehospital early warning scores to predict short-term mortality: A systematic review.Emergency medicine Australasia : EMA · 2025Pooled it
- Ketamine versus etomidate as an induction agent for tracheal intubation in critically ill adults: a Bayesian meta-analysis.Critical care (London, England) · 2024Pooled it
- Resource use, availability and cost in the provision of critical care in Tanzania: a systematic review.BMJ open · 2022Pooled it
- A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed.Nature communications · 2023Trial
- Research priorities for intensive care: A stakeholder-informed priority-setting partnership.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- One in seven has severe pain: a point-prevalence study of hospitalised patients across Africa.Pain · 2026Article
- Article
- Diagnostic capability of large language models in critically ill patients: a prospective single-centre study comparing ChatGPT, Claude, and Gemini with emergency physicians.BMC emergency medicine · 2026Observational
- Clinical implications of ferroptosis in critical illness: a narrative review.Journal of intensive care · 2026Review
- "It Is Humble but Honorable Work": A Needs Assessment of Critical Care Education in the Pediatric Residency Programs of Honduras.Journal of graduate medical education · 2026Article
- Nursing interventions to ensure the safety of critically ill patients in intrahospital transportation: A scoping review.Journal of the Intensive Care Society · 2026Review
- Developing consensus-based indicators for intensive care unit capacity and capability in South Korea: a modified Delphi study.Acute and critical care · 2026Article
- A core outcome set and reporting checklist for research on critically ill obstetric patients: An international consensus study.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Systematic literature review on biopsychosocial factors in the surgical waiting list.Clinics (Sao Paulo, Brazil) · 2026Review
- Critical illness in prisons: a multi-methods analysis of reported healthcare safety incidents in England.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026Article
- Time-critical care gaps and systemic delays linked to higher mortality in severe trauma patients in Tanzania.BMC emergency medicine · 2026Observational
- A Double-Edged Sword: How Clinical Context Shapes Clinicians' Perceptions of Parental Religion in Paediatric Critical Care.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Systemic inflammatory markers as a supplement to nutrition risk screening of ICU patients.Asia Pacific journal of clinical nutrition · 2026Article
- Examining concepts related to critical illness and the management of critically ill patients: a protocol for a scoping review.NIHR open research · 2026Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAs 'critical illness' and 'critical care' lack consensus definitions, this study aimed to explore how the concepts' are used, describe their defining attributes, and propose potential definitions. DESIGN AND
methodsWe used the Walker and Avant approach to concept analysis. The uses and definitions of the concepts were identified through a scoping review of the literature and an online survey of 114 global clinical experts. We used the Arksey and O'Malley framework for scoping reviews and searched in PubMed and Web of Science with a strategy including terms around critical illness/care and definitions/etymologies limited to publications in English between 1 January 2008 and 1 January 2020. The experts were selected through purposive sampling and snowballing, with 36.8% in Africa, 25.4% in Europe, 22.8% in North America, 10.5% in Asia, 2.6% in South America and 1.8% in Australia. They worked with anaesthesia or intensive care 59.1%, emergency care 15.8%, medicine 9.5%, paediatrics 5.5%, surgery 4.7%, obstetrics and gynaecology 1.6% and other specialties 3.9%. Through content analysis of the data, we extracted codes, categories and themes to determine the concepts' defining attributes and we proposed potential definitions. To assist understanding, we developed model, related and contrary cases concerning the concepts, we identified antecedents and consequences to the concepts, and defined empirical referents.
resultsNine and 13 articles were included in the scoping reviews of critical illness and critical care, respectively. A total of 48 codes, 14 categories and 4 themes were identified in the uses and definitions of critical illness and 60 codes, 13 categories and 5 themes for critical care. The defining attributes of critical illness were a high risk of imminent death; vital organ dysfunction; requirement for care to avoid death; and potential reversibility. The defining attributes of critical care were the identification, monitoring and treatment of critical illness; vital organ support; initial and sustained care; any care of critical illness; and specialised human and physical resources. The defining attributes led to our proposed definitions of critical illness as, 'a state of ill health with vital organ dysfunction, a high risk of imminent death if care is not provided and the potential for reversibility', and of critical care as, 'the identification, monitoring and treatment of patients with critical illness through the initial and sustained support of vital organ functions.'
conclusionThe concepts critical illness and critical care lack consensus definitions and have varied uses. Through concept analysis of uses and definitions in the literature and among experts, we have identified the defining attributes of the concepts and proposed definitions that could aid clinical practice, research and policy-making.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.