Evidence map›Paper›PMID 36606648›Full record

ArticleJournal of clinical neurology (Seoul, Korea)2023

Predictive Value of Exercise Blood Pressure Changes for Orthostatic Hypotension in Patients With Parkinson's Disease.

Yi Qin, Zhao-Hui Jin, Zhen-Ying Zhang, Ke-Ke Chen, Xin Yu, Hong-Jiao Yan, Rui-Dan Wang, Yuan Su, Ai-Xian Liu, Jia-Ning Xi and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical neurology (Seoul, Korea), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Prevalence and impact of orthostatic hypotension in Parkinson's disease: a systematic review and meta-analysis.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yi QinBeijing Rehabilitation Medical College, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-6563-1431
Zhao-Hui JinParkinson Medical Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-2079-8059
Zhen-Ying ZhangCardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-0856-2991
Ke-Ke ChenBeijing Rehabilitation Medical College, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-3094-1306
Xin YuBeijing Rehabilitation Medical College, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-5649-6290
Hong-Jiao YanParkinson Medical Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0001-6800-599X
Rui-Dan WangParkinson Medical Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-1630-6691
Yuan SuParkinson Medical Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-5119-594X
Ai-Xian LiuParkinson Medical Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-4303-5348
Jia-Ning XiParkinson Medical Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-3723-0478
Bo-Yan FangParkinson Medical Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China. fangboyanv@163.com.ORCID https://orcid.org/0000-0002-9935-433X
Capital Medical University · CN

Funding

Beijing Rehabilitation Hospital, Capital Medical University 2019R-006Beijing Rehabilitation Hospital, Capital Medical University 2020-051Beijing Rehabilitation Hospital, Capital Medical University 2020-069National Key Research and Development Program of China 2018YFC0115405
6 · The paper itself

Abstract

background and purposeOrthostatic hypotension (OH) is common in patients with Parkinson's disease (PD). Early recognition OH is required with sensitive assessments. The purpose of this study was to determine whether blood pressure (BP) changes during exercise can predict the occurrence of OH in PD.

methodsThis prospective cohort study included 80 consecutive patients with PD. All patients agreed to participate in a baseline evaluation and cardiopulmonary exercise test (CPET). According to the initial active standing test (AST), those without OH (PD-nonOH) at baseline had their AST results followed up for 6 months. The main outcome was defined as whether patients without OH at baseline would develop OH after 6 months. Logistic regression analysis was applied to identify the relevant variables. A nomogram was constructed based on clinical features and identified variables. The concordance index (C-index) and area under the receiver operating characteristic curve (AUC) were used to evaluate the accuracy and predictive ability of the nomogram, respectively.

resultsCPET results indicated that peak load, peak heart rate, heart rate recovery at 1 min, and systolic BP change (ΔSBP) were lower in those with OH than in the PD-nonOH group (

conclusionsThis study has identified predictive factors for OH development in patients with PD. CPET could be used as a complementary examination to identify patients at a high risk of OH.

Indexed as

cardiopulmonary exercise testexercise blood pressureorthostatic hypotensionParkinson's disease

Identifiers

PMID36606648
PMCPMC9833883
OpenAlexW4313470838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.