Evidence map›Paper›PMID 36606348›Full record

ArticleBipolar disorders2023

Detailed assessment of suicidal ideation in youth with bipolar disorder versus major depressive disorder.

Rebekah S Huber, Danielle Boxer, Calen J Smith, Perry F Renshaw, Deborah A Yurgelun-Todd, Douglas G Kondo

Abstract read
In one paragraph

Article in Bipolar disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rebekah S HuberDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA.ORCID 0000-0002-6718-9683
Danielle BoxerDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Calen J SmithDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Perry F RenshawDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Deborah A Yurgelun-ToddDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Douglas G KondoDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA.

Funding

Dietary Supplement Creatine for Adolescent Females with SSRI-Resistant DepressionR33MH096858 · NIMH · UNIVERSITY OF UTAH · PI RENSHAW, PERRY FRANKLIN · 2014 to 2016
$703k
Dietary Supplement Creatine for Adolescent Females with SSRI-Resistant DepressionR21MH096858 · NIMH · UNIVERSITY OF UTAH · PI RENSHAW, PERRY FRANKLIN · 2012 to 2013
$433k
NIMH NIH HHS R21 MH096858NIMH NIH HHS R33 MH096858
6 · The paper itself

Abstract

objectivesThere is a critical need to better understand the factors underlying the increased suicide risk for youth with bipolar disorder (BD) in order to develop targeted prevention efforts. This study aimed to examine differences in characteristics of suicide ideation (SI) in youth with BD compared to youth with major depressive disorder (MDD) that may be associated with increased suicide risk.

methodsOne hundred and fifty-one participants (92 MDD and 59 BD), ages 13-21, completed a diagnostic interview and clinical assessments. Lifetime symptoms of SI and SA were assessed using the Columbia Suicide Severity Rating Scale. Ordinal logistic regression models were used to investigate whether the diagnostic group predicted the severity and intensity of the most severe or most common SI with the age of onset, age, and gender as covariates.

resultsCompared to MDD youth, BD youth were more likely to report experiencing more severe SI, p = 0.039, experiencing the most severe SI more frequently, p = 0.002, having less control of the most severe SI, p = 0.012, and that deterrents were less likely to stop them from acting on the most severe SI, p = 0.006.

conclusionThis study highlights differences in the severity and intensity of SI in youth with BD and suggests that youth with BD have greater difficulty inhibiting thoughts of SI which may lead to less resistance to suicide action. Findings underscore the need for a more detailed assessment of SI in youth with BD to better understand SI as a proximal risk factor for future SA and a potential target for intervention.

Indexed as

Bipolar DisorderMajor Depressive DisorderAdolescentHumansLogistic ModelsRisk FactorsSuicidal Ideationbipolar disorderC-SSRSmajor depressive disordersuicidal ideationsuicide assessmentsuicide attemptsuicide risktreatment-resistant depressionyouth

Identifiers

PMID36606348
PMCPMC10525907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.