Evidence map›Paper›PMID 36606165›Full record

ArticleMalaysian family physician : the official journal of the Academy of Family Physicians of Malaysia2022

Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: A cross-sectional study.

Hui Zhu Thew, Siew Mooi Ching, Hooi Min Lim, Mike Hitler Mos, Lorna Chin Kin Tze, Kui Feng Low, Nurdarlina Shaari, Jody Yii Sze Lin, Kai Wei Lee, Vasudevan Ramachandran

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Article in Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hui Zhu ThewMD (NNSMA), MMed (UPM), Department of Family Medicine, Faculty Medicine and Health Sciences, Serdang, Malaysia.
Siew Mooi ChingMD (UNIMAS), MMed (UM), Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.
Hooi Min LimMBBS (UM), MMed (UM), Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Mike Hitler MosMBBS (UM), Klinik Kesihatan Batu Kawa, Jalan Ensing Timur, Off Jalan, Stapok Utama,Kuching, Sarawak, Malaysia.
Lorna Chin Kin TzeMD (UPM), MAFP, FRACGP, Klinik Kesihatan Miri, Jalan Merbau, Miri, Sarawak, Malaysia.
Kui Feng LowMD, Klinik Kesihatan Jalan Masjid, Jalan Masjid, Kuching, Sarawak, Malaysia.
Nurdarlina ShaariMBBS(UM), MAFP, FRACGP, Klinik Kesihatan Telaga Air, Jalan Matang, Kuching, Sarawak, Malaysia.
Jody Yii Sze LinMD (UNIMAS), MAFP, FRACGP, Klinik Kesihatan Tudan, Jalan Permyjaya, Miri, Sarawak, Malaysia.
Kai Wei LeePh.D. (UPM), Department of Medical Microbiology, Faculty of Medicine and Health Sciences, Universiti Putra, Malaysia, Serdang, Malaysia.
Vasudevan RamachandranPh.D. (UPM), Faculty of Health Sciences, University College MAIWP, International College, Taman Batu, Muda, Batu Caves, Kuala Lumpur, Malaysia.
Universiti Putra Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Non-adherence to antihypertensive medications is a leading cause of uncontrolled hypertension and its complications. However, data on the factors associated with non-adherence to antihypertensive medications in the communities of Sarawak, Malaysia, are limited. This study aimed to examine the prevalence and determinants of medication non-adherence among patients with uncontrolled hypertension. Method: A cross-sectional study was conducted using the systematic sampling method in four government primary healthcare clinics in Sarawak. A self-administered questionnaire was used to obtain socio-demographic data and evaluate non-adherence. Blood pressure was measured, and relevant clinical variables were collected from medical records. Multivariate logistic regression was used to determine the determinants of medication non-adherence. Results: A total of 488 patients with uncontrolled hypertension were enrolled in this study. The prevalence of medication non-adherence was 39.3%. There were four predictors of medication non-adherence among the patients with uncontrolled hypertension: tertiary educational level (odds ratio [OR]=4.21, 95% confidence interval [CI] = 1.67-10.61, P=0.010), complementary alternative medication (0R=2.03, 95% CI=1.12-3.69, P=0.020), non-usage of calcium channel blockers (0R=1.57, 95% CI=1.02-2.41, P=0.039) and 1 mmHg increase in the systolic blood pressure (0R=1.03, 95% CI=1.00-1.05, P=0.006). Conclusion: Because of the high prevalence of medication non-adherence among patients with uncontrolled hypertension, primary care physicians should be more vigilant in identifying those at risk of being non-adherent. Early intervention should be conducted to address non-adherence for blood pressure control.

Indexed as

HypertensionMalaysiaPatient compliancePrimary health care

Identifiers

PMID36606165
PMCPMC9809434
OpenAlexW4310736189

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.