Evidence map›Paper›PMID 36606008›Full record

ArticleMiddle East journal of digestive diseases2021

Colonic Mucosal Infiltration of IgG4 Plasma Cells and Ulcerative Colitis: Determinant of Presence, Activity, Extension, and Duration of Disease.

Foroogh Alborzi, Nasser Ebrahimi Daryani, Tina Deihim, Zahra Azizi, Farid Azmoudeh Ardalan, Azam Teimouri, Reza Taslimi, Nader Roshan, Masood Mami, Monirsadat Mirzade and 1 more

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In one paragraph

Article in Middle East journal of digestive diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Foroogh AlborziAssistant Professor of Gastroenterology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Nasser Ebrahimi DaryaniProfessor of Gastroenterology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Tina DeihimInternal Medicine Resident, Internal Medicine Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Zahra AziziResearcher, Iran University of Medical Sciences, Tehran, Iran.
Farid Azmoudeh ArdalanPathologist, Associate Professor of Tehran University of Medical Sciences, Tehran, Iran.
Azam TeimouriAssistant Professor of Gastroenterology, Isfahan University of Medical Sciences, Isfahan, Iran.
Reza TaslimiAssistant Professor of Gastroenterology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Nader RoshanAssociate Professor of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran.
Masood MamiAssistant Professor of Gastroenterology, Ilam University of Medical Sciences, Ilam, Iran.
Monirsadat MirzadeResident of Community Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.
Najmeh AletahaAssociate Professor of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRImam Khomeini Hospital · IRBushehr University of Medical Sciences · IRIran University of Medical Sciences · IRIsfahan University of Medical Sciences · IRMedical University of Ilam · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Infiltration of IgG4 positive plasma cells has been detected in the colonic mucosa of patients with ulcerative colitis (UC). The aim of the study was to investigate the association between colonic mucosal infiltration of IgG4 plasma cells and the presence, activity, extension, and duration of UC. METHODS In this case-control study (2009-2014), 102 subjects (84 with UC/18 controls) were enrolled. Clinical records and rectosigmoid biopsies of UC patients were selected, and biopsies were stained with IgG4 monoclonal antibodies. IgG4 positive plasma cells were counted by a single pathologist. RESULTS Amongst 84 patients with UC, 73.8% had UC without primary sclerosing cholangitis (PSC), and 26.2% had UC with PSC. IgG4 plasma cells were seen in 35 (41.7%) patients with UC and 0% of controls (

Indexed as

Disease activityDuration of diseaseExtension of diseaseIgG4 plasma cellsPrimary sclerosing cholangitisUlcerative colitis

Identifiers

PMID36606008
PMCPMC9489443
OpenAlexW4210705277

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.