Evidence map›Paper›PMID 36605937›Full record

ArticleFrontiers in endocrinology2022

Follicle-stimulating hormone and blood lead levels with bone mineral density and the risk of fractures in pre- and postmenopausal women.

Huixin Tong, Bo Su, Zhize Liu, Yongjie Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Huixin TongDepartment of Endocrinology, General Hospital of Northern Theater Command, Shenyang, China.
Bo SuDepartment of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhize LiuDepartment of Orthopedics, Dalian Municipal Central Hospital, Dalian, China.
Yongjie ChenDepartment of Epidemiology and Statistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Dalian Municipal Central Hospital · CNGeneral Hospital of Shenyang Military Region · CNHarbin Medical University · CNTianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The conclusions on the associations of serum follicle-stimulating hormone (FSH) and blood lead levels with bone mineral density (BMD) were controversial. Furthermore, little was known on the impacts of co-existence of serum FSH and blood lead levels on BMD and the risk of fractures in premenopausal and postmenopausal women. Therefore, the present study aimed to examine the associations of serum FSH and blood lead levels with BMD and the risk of fractures in premenopausal and postmenopausal women. Methods: Data were derived from the National Health and Nutrition Examination Survey. FSH is assayed using the Microparticle Enzyme Immunoassay technology. Blood lead levels were measured using atomic absorption spectrometry. BMD was measured using dual energy X-ray absorptiometry. Fractures were defined as subjects with fractures in any site of hip, wrist, and spine. Results: This study included 3798 participants. Elevated blood lead levels were associated with increased serum FSH levels ( Conclusions: Serum lead levels were associated with serum FSH levels. Serum FSH levels were associated with a lower BMD and a higher risk of fractures.

Indexed as

Bone DensityFractures, BoneFemaleFollicle Stimulating HormoneFollicle Stimulating Hormone, HumanHumansLeadNutrition SurveysPostmenopauseFollicle Stimulating HormoneFollicle Stimulating Hormone, HumanLeadblood lead levelsbone mineral densityfollicle-stimulating hormonefractures – bonemenopause

Identifiers

PMID36605937
PMCPMC9810013
OpenAlexW4311948841

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.