Evidence map›Paper›PMID 36605795›Full record

ArticleNanoscale advances2022

Ultrasmall porphyrin-silica core-shell dots for enhanced fluorescence imaging-guided cancer photodynamic therapy.

Sadaf Hameed, Pravin Bhattarai, Zhuoran Gong, Xiaolong Liang, Xiuli Yue, Zhifei Dai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. A Review of Silica-Based Nanoplatforms for Anticancer Cargo Delivery.International journal of molecular sciences · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Sadaf HameedFaculty of Science and Technology, University of Central Punjab Lahore 54000 Pakistan.ORCID https://orcid.org/0000-0001-9578-3201
Pravin BhattaraiCÚRAM-SFI Research Centre for Medical Devices, Biomedical Sciences, University of Galway Ireland.
Zhuoran GongDepartment of Biomedical Engineering, College of Future Technology, Peking University Beijing 100871 China zhifei.dai@pku.edu.cn.
Xiaolong LiangDepartment of Ultrasonography, Peking University Third Hospital Beijing 100191 China.ORCID https://orcid.org/0000-0001-7299-3329
Xiuli YueSchool of Environment, Harbin Institute of Technology Harbin 150001 China xiulidx@163.com.
Zhifei DaiDepartment of Biomedical Engineering, College of Future Technology, Peking University Beijing 100871 China zhifei.dai@pku.edu.cn.ORCID https://orcid.org/0000-0002-8283-3190
Peking University · CNHarbin Institute of Technology · CNUniversity Hospital Galway · IEUniversity of Central Punjab · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinically used small-molecular photosensitizers (PSs) for photodynamic therapy (PDT) share similar disadvantages, such as the lack of selectivity towards cancer cells, short blood circulation time, life-threatening phototoxicity, and low physiological solubility. To overcome such limitations, the present study capitalizes on the synthesis of ultra-small hydrophilic porphyrin-based silica nanoparticles (core-shell porphyrin-silica dots; PSDs) to enhance the treatment outcomes of cancer

Identifiers

PMID36605795
PMCPMC9765644
OpenAlexW4313431048

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.