Evidence map›Paper›PMID 36605695›Full record

ArticleIJU case reports2023

Primary lung cancer treatable with radical resection after complete remission with pembrolizumab therapy following gemcitabine and carboplatin chemotherapy for multiple metastases of bladder cancer.

Ryohta Nakamura, Go Hasegawa, Kazumasa Ohashi, Takehisa Hashimoto, Yohei Ikeda, Noboru Hara, Tsutomu Nishiyama

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ryohta NakamuraDepartment of Urology, Uonuma Institute of Community Medicine Niigata University Medical and Dental Hospital Minamiuonuma Niigata Japan.
Go HasegawaDepartment of Pathology, Uonuma Institute of Community Medicine Niigata University Medical and Dental Hospital Minamiuonuma Niigata Japan.
Kazumasa OhashiDepartment of Respiratory Medicine, Uonuma Institute of Community Medicine Niigata University Medical and Dental Hospital Minamiuonuma Niigata Japan.
Takehisa HashimotoDepartment of Respiratory Surgery, Uonuma Institute of Community Medicine Niigata University Medical and Dental Hospital Minamiuonuma Niigata Japan.
Yohei IkedaDepartment of Diagnostic Radiology, Uonuma Institute of Community Medicine Niigata University Medical and Dental Hospital Minamiuonuma Niigata Japan.
Noboru HaraDepartment of Urology, Uonuma Institute of Community Medicine Niigata University Medical and Dental Hospital Minamiuonuma Niigata Japan.ORCID https://orcid.org/0000-0003-3985-0603
Tsutomu NishiyamaDepartment of Urology, Uonuma Institute of Community Medicine Niigata University Medical and Dental Hospital Minamiuonuma Niigata Japan.ORCID https://orcid.org/0000-0002-5684-8364
Niigata University Medical and Dental Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: We report a patient with the complete remission of multiple metastases and primary bladder lesions of bladder cancer who developed primary lung cancer requiring radical resection. Case presentation: A 68-year-old man diagnosed with invasive bladder cancer, right hydroureteronephrosis, and multiple metastases were administered six courses of gemcitabine and carboplatin chemotherapy and thereafter has been receiving pembrolizumab therapy. Bladder cancer and multiple metastases decreased in size, whereas a ground-glass opacity lesion in the lung gradually increased in size. Fluorodeoxyglucose-positron emission tomography revealed the accumulation of fluorodeoxyglucose in the ground-glass opacity lesion only. The patient was diagnosed with primary lung cancer and underwent a thoracoscopic lobectomy. Histopathological findings showed ALK-negative, EGFR L858R mutation-positive invasive adenocarcinoma with a programmed death-ligand 1 tumor proportion score of less than 1%. Conclusion: This is the first case report of patients with the complete remission of multiple metastases of bladder cancer who developed primary lung cancer requiring radical resection.

Indexed as

advanced bladder cancerpembrolizumab therapy following gemcitabine and carboplatin chemotherapy with complete remissionprimary lung cancer with radical resection

Identifiers

PMID36605695
PMCPMC9807337
OpenAlexW4308796305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.