Evidence map›Paper›PMID 36605681›Full record

ArticleIJU case reports2023

A case of hypogonadtropic hypogonadism due to hypophysitis discovered by secondary male infertility.

Masatoshi Konishi, Yoko Maegawa, Masaru Tani, Toshihisa Asakura, Yujiro Hayashi, Yoichi Kakuta, Koichi Tsutahara, Kazuhiko Komori, Tetsuya Takao

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Masatoshi KonishiDepartment of Urology Osaka General Medical Center Osaka Japan.ORCID https://orcid.org/0000-0002-6058-9916
Yoko MaegawaDepartment of Urology Osaka General Medical Center Osaka Japan.
Masaru TaniDepartment of Urology Osaka General Medical Center Osaka Japan.
Toshihisa AsakuraDepartment of Urology Osaka General Medical Center Osaka Japan.
Yujiro HayashiDepartment of Urology Osaka General Medical Center Osaka Japan.
Yoichi KakutaDepartment of Urology Osaka General Medical Center Osaka Japan.
Koichi TsutaharaDepartment of Urology Osaka General Medical Center Osaka Japan.
Kazuhiko KomoriKomori Clinic Osaka Japan.
Tetsuya TakaoDepartment of Urology Osaka General Medical Center Osaka Japan.
Osaka Prefectural Medical Center · JPOsaka Nishi Clinic · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The main causes of secondary male infertility are varicocele and aging. It is rarely caused by adult-onset hypopituitarism. The onset of hypopituitarism is often due to brain tumors, trauma, surgery, or congenital disorders. Case presentation: A 29-year-old man was admitted to the hospital with complaints of decreased libido and semen volume, which lasted for 4 months. He had no abnormalities in adolescence and has a 2-year-old child. Blood tests showed low luteinizing hormone and follicle-stimulating hormone, and semen tests showed azoospermia. Magnetic resonance imaging T1-weighted images showed swelling and enhancement effect of the pituitary gland, and lymphocytic hypophysitis was suspected. After an Insulin-thyroid-stimulating hormone releasing hormone-luteinizing hormone-releasing hormone test, a decrease in luteinizing hormone/follicle-stimulating hormone secretion was considered. We diagnosed hypogonadotropic hypogonadism due to lymphocytic hypophysitis. Currently, the patient is being treated with a hormone replacement therapy. Conclusion: We experienced a case of hypogonadotropic hypogonadism due to lymphocytic hypophysitis discovered by secondary infertility.

Indexed as

hormone replacement therapyhypogonadtropic hypogonadismhypophysitissecondary male infertility

Identifiers

PMID36605681
PMCPMC9807335
OpenAlexW4307066829

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.