Evidence map›Paper›PMID 36605560›Full record

ReviewInternational journal of nanomedicine2022

Antibacterial Pathways in Transition Metal-Based Nanocomposites: A Mechanistic Overview.

Chinmaya Mutalik, I-Hsin Lin, Dyah Ika Krisnawati, Siti Khaerunnisa, Muhamad Khafid, Widodo, Yu-Cheng Hsiao, Tsung-Rong Kuo

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Recent Advances in Nanoparticle-Mediated Antibacterial Photodynamic Therapy.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review of Antimicrobial Properties of Titanium Dioxide Nanoparticles.International journal of molecular sciences · 2024
    Review
  12. Article
  13. Article
  14. TiRSC advances · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Gold-Based Nanostructures for Antibacterial Application.International journal of molecular sciences · 2023
    Review
  20. Metal-Based Nanoparticles: A Prospective Strategy forInternational journal of nanomedicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Chinmaya MutalikInternational Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.
I-Hsin LinSchool of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.
Dyah Ika KrisnawatiDharma Husada Nursing Academy, Kediri, Indonesia.
Siti KhaerunnisaDepartment of Physiology and Medical Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.ORCID 0000-0002-6358-8265
Muhamad KhafidDepartment of Nursing, Faculty of Nursing and Midwifery, Universitas Nahdlatul Ulama Surabaya, East Java, Indonesia.
WidodoCollege of Information System, Universitas Nusantara PGRI, Kediri, Indonesia.
Yu-Cheng HsiaoInternational Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.
Tsung-Rong KuoInternational Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.ORCID 0000-0003-4937-951X
Taipei Medical University · TWAirlangga University · IDUniversitas Dharmas Indonesia · IDUniversitas Nahdlatul Ulama Indonesia · IDUniversitas Nusantara PGRI KediriWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Across the planet, outbreaks of bacterial illnesses pose major health risks and raise concerns. Photodynamic, photothermal, and metal ion release effects of transition metal-based nanocomposites (TMNs) were recently shown to be highly effective in reducing bacterial resistance and upsurges in outbreaks. Surface plasmonic resonance, photonics, crystal structures, and optical properties of TMNs have been used to regulate metal ion release, produce oxidative stress, and generate heat for bactericidal applications. The superior properties of TMNs provide a chance to investigate and improve their antimicrobial actions, perhaps leading to therapeutic interventions. In this review, we discuss three alternative antibacterial strategies based on TMNs of photodynamic therapy, photothermal therapy, and metal ion release and their mechanistic actions. The scientific community has made significant efforts to address the safety, effectiveness, toxicity, and biocompatibility of these metallic nanostructures; significant achievements and trends have been highlighted in this review. The combination of therapies together has borne significant results to counter antimicrobial resistance (4-log reduction). These three antimicrobial pathways are separated into subcategories based on recent successes, highlighting potential needs and challenges in medical, environmental, and allied industries.

Indexed as

Anti-Infective AgentsNanocompositesTransition ElementsAnti-Bacterial AgentsMetalsAnti-Bacterial AgentsAnti-Infective AgentsMetalsTransition Elementsantibacterial mechanismsmetal ion releasenanocompositesphotodynamicphotothermaltransition metals

Identifiers

PMID36605560
PMCPMC9809169
OpenAlexW4313317309

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.