Evidence map›Paper›PMID 36605557›Full record

ArticleFrontiers in neuroscience2022

Mechanism of extracellular space changes in cryptococcal brain granuloma revealed by MRI tracer.

Nuerbiyemu Abulikemu, Xin Gao, Wei Wang, Qingyuan He, Gang Wang, Tao Jiang, Xiaodong Wang, Yumeng Cheng, Min Chen, Yanran Li and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Nuerbiyemu AbulikemuImaging Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Xin GaoShanghai Universal Medical Imaging Diagnostic Center, Shanghai University, Shanghai, China.
Wei WangDepartment of Rehabilitation Radiology, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Qingyuan HeBeijing Key Laboratory of Magnetic Resonance Imaging Devices and Technology, Peking University Third Hospital, Beijing, China.
Gang WangImaging Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Tao JiangThe Animal Experimental Center, Xinjiang Medical University, Ürümqi, China.
Xiaodong WangDepartment of Dermatology, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Yumeng ChengBeijing Key Laboratory of Magnetic Resonance Imaging Devices and Technology, Peking University Third Hospital, Beijing, China.
Min ChenDepartment of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Yanran LiImaging Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Lulu LiuImaging Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Jingjing ZhaoImaging Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Jin LiImaging Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Chunhui JiangImaging Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Yunling WangImaging Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Hongbin HanBeijing Key Laboratory of Magnetic Resonance Imaging Devices and Technology, Peking University Third Hospital, Beijing, China.
Jian WangImaging Center, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
First Affiliated Hospital of Xinjiang Medical University · CNXinjiang Medical University · CNPeking University Third Hospital · CNCapital Medical University · CNPeking University · CNSecond Military Medical University · CNShanghai University of Medicine and Health Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to investigate the changes in extracellular space (ECS) in cryptococcal brain granuloma and its pathological mechanism. Materials and methods: The animal model of cryptococcal brain granuloma was established by injecting 1 × 10 Results: Up to 28 days of modeling, the success rate of establishing the brain cryptococcal granuloma model with 1 × 10 Conclusion: The internal area of the lesion demonstrated a quicker, broader, and more extended distribution of the tracer, while the edge of the lesion exhibited a slower and narrower distribution. MRI tracer method can monitor morphological and functional changes of ECS in pathological conditions and provide a theoretical basis for the treatment

Indexed as

braincryptococcal granulomaextracellular spacemechanismMRI tracer

Identifiers

PMID36605557
PMCPMC9808069
OpenAlexW4313435413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.