Evidence map›Paper›PMID 36605025›Full record

ArticlePediatric obesity2023

Prenatal weight and regional body composition trajectories and neonatal body composition: The NICHD Foetal Growth Studies.

Elizabeth M Widen, Natalie Burns, Linda G Kahn, Jagteshwar Grewal, Grant Backlund, Amy R Nichols, Rachel Rickman, Saralyn Foster, Chia-Ling Nhan-Chang, Cuilin Zhang and 8 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric obesity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 1 country.

Elizabeth M WidenDepartment of Nutritional Sciences, University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0002-9574-6109
Natalie BurnsDepartment of Statistics, University of Florida, Gainesville, Florida, USA.
Linda G KahnDepartments of Pediatrics and Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Jagteshwar GrewalDivision of Population Health Research, Division of Intramural Research, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA.
Grant BacklundDepartment of Statistics, University of Florida, Gainesville, Florida, USA.
Amy R NicholsDepartment of Nutritional Sciences, University of Texas at Austin, Austin, Texas, USA.
Rachel RickmanDepartment of Nutritional Sciences, University of Texas at Austin, Austin, Texas, USA.
Saralyn FosterDepartment of Nutritional Sciences, University of Texas at Austin, Austin, Texas, USA.
Chia-Ling Nhan-ChangDepartment of Obstetrics and Gynecology, Columbia University Medical Center, Columbia, South Carolina, USA.
Cuilin ZhangDivision of Population Health Research, Division of Intramural Research, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA.
Ronald WapnerDepartment of Obstetrics and Gynecology, Columbia University Medical Center, Columbia, South Carolina, USA.
Deborah A WingDivision of Maternal-Fetal Medicine, Department of Obstetrics-Gynecology, University of California, Irvine, School of Medicine, Irvine, and Fountain Valley Regional Hospital and Medical Center, Fountain Valley, California, USA.
John OwenDivision of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Daniel W SkupskiDepartment of Obstetrics and Gynecology, New York-Presbyterian Queens Hospital, Queens, New York, USA.
Angela C RanziniDivision of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, St Peter's University Hospital, New Brunswick, New Jersey, USA.
Roger NewmanDepartment of Obstetrics and Gynecology, Medical University of South Carolina, Columbia, South Carolina, USA.
William GrobmanDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University (WAG), New Rochelle, New York, USA.
Michael J DanielsDepartment of Statistics, University of Florida, Gainesville, Florida, USA.
The University of Texas at Austin · USUniversity of Florida · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USUniversity of South Carolina · USMedical University of South Carolina · USNew York Hospital Queens · USNew York University · USNorthwestern University · USSaint Peter's University Hospital · USUniversity of Alabama at Birmingham · USUniversity of California, Irvine · US

Funding

Population Research CenterR24HD042849 · NICHD · UNIVERSITY OF TEXAS AUSTIN · PI HAYWARD, MARK D. · 2002 to 2016
$8.4M
Scientific & Technical CoreP2CHD042849 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI Elizabeth T. Gershoff · 2017 to 2026
$5.2M
Nonpersistent chemical exposure, placental development, and maternal pre- and post-pregnancy cardiovascular healthR00ES030403 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KAHN, LINDA G · 2022 to 2024
$746k
Pregnancy weight trajectories and offspring adiposityR00HD086304 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI WIDEN, ELIZABETH MARIE · 2018 to 2020
$744k
Pregnancy weight trajectories and offspring adiposityK99HD086304 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI WIDEN, ELIZABETH MARIE · 2016 to 2017
$258k
Nonpersistent chemical exposure, placental development, and maternal pre- and post-pregnancy cardiovascular healthK99ES030403 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KAHN, LINDA G · 2019 to 2020
$220k
NICHD NIH HHS HHSN275200800002CNICHD NIH HHS HHSN275200800002INICHD NIH HHS HHSN275200800003CNICHD NIH HHS HHSN275200800003INICHD NIH HHS HHSN275200800012CNICHD NIH HHS HHSN275200800013CNICHD NIH HHS HHSN275200800014CNICHD NIH HHS HHSN275200800028CNICHD NIH HHS HHSN275200800031CNICHD NIH HHS HHSN275201000009CNICHD NIH HHS K99 HD086304NICHD NIH HHS P2C HD042849NICHD NIH HHS R00 HD086304NICHD NIH HHS R24 HD042849NIEHS NIH HHS K99 ES030403NIEHS NIH HHS R00 ES030403
6 · The paper itself

Abstract

backgroundGestational weight gain (GWG) and anthropometric trajectories may affect foetal programming and are potentially modifiable.

objectivesTo assess concomitant patterns of change in weight, circumferences and adiposity across gestation as an integrated prenatal exposure, and determine how they relate to neonatal body composition.

methodsData are from a prospective cohort of singleton pregnancies (n = 2182) enrolled in United States perinatal centres, 2009-2013. Overall and by prepregnancy BMI group (overweight/obesity and healthy weight), joint latent trajectory models were fit with prenatal weight, mid-upper arm circumference (MUAC), triceps (TSF) and subscapular (SSF) skinfolds. Differences in neonatal body composition by trajectory class were assessed via weighted least squares.

resultsSix trajectory patterns reflecting co-occurring changes in weight and MUAC, SSF and TSF across pregnancy were identified overall and by body mass index (BMI) group. Among people with a healthy weight BMI, some differences were observed for neonatal subcutaneous adipose tissue, and among individuals with overweight/obesity some differences in neonatal lean mass were found. Neonatal adiposity measures were higher among infants born to individuals with prepregnancy overweight/obesity.

conclusionsSix integrated trajectory patterns of prenatal weight, subcutaneous adipose tissue and circumferences were observed that were minimally associated with neonatal body composition, suggesting a stronger influence of prepregnancy BMI.

Indexed as

OverweightWeight GainBody CompositionBody Mass IndexFemaleFetal DevelopmentHumansInfantInfant, NewbornNational Institute of Child Health and Human Development (U.S.)ObesityPregnancyProspective StudiesUnited Statesadipositybody compositiongestational weight gaininfancylatent class analysispregnancytrajectory modelling

Identifiers

PMID36605025
PMCPMC9924063
OpenAlexW4313648554

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.