SynthesisJournal of cachexia, sarcopenia and muscle2023
Recent sarcopenia definitions-prevalence, agreement and mortality associations among men: Findings from population-based cohorts.
Synthesis in Journal of cachexia, sarcopenia and muscle, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07255001 (Monitoring Physical Function Changes in Patients With Pancreatic Ductal Adenocarcinoma), which is not on this map. Cited by 61 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Monitoring Physical Function Changes in Patients With Pancreatic Ductal Adenocarcinoma: Potential for Better Understanding of Treatment Trajectory and Survival
Who cites it
61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- The association between muscle mass and change in physical functioning in older adults: a systematic review and meta-analysis of prospective studies.European geriatric medicine · 2025Pooled it
- Prevalence and Risk of Sarcopenia in Patients with Chronic Pancreatitis: Systematic Review and Meta-Analysis.Nutrients · 2025Pooled it
- Sarcopenia interventions in long-term care facilities targeting sedentary behaviour and physical inactivity: A systematic review.Journal of cachexia, sarcopenia and muscle · 2024Pooled it
- Recent sarcopenia definitions-prevalence, agreement and mortality associations among men: Findings from population-based cohorts.Journal of cachexia, sarcopenia and muscle · 2023Pooled it
- Fermented protein foods as modulators of the gut-muscle axis: mechanisms, evidence, and future directions.Communications biology · 2026Review
- Multidomain changes in clinical outcomes after 12 weeks of resistance-based exercise training in healthy older adults: a four‑domain framework for identifying non‑responders.European geriatric medicine · 2026Article
- Sparing Muscle While Losing Fat: A Narrative Review of Ketogenic Diets and Lean Mass Preservation During Weight Loss.Nutrients · 2026Review
- Longitudinal changes in body composition and obstructive sleep apnea severity among older men: the Osteoporotic Fractures in Men (MrOS) sleep study.Annals of the American Thoracic Society · 2026Article
- Prognostic performance of Asian Working Group for Sarcopenia 2025 Constructs for activities of daily living at discharge after stroke: a head-to-head validation.European geriatric medicine · 2026Article
- Sarcopenia, an independent predictor for all-cause mortality in rheumatoid arthritis: Insights from the NHANES database.Medicine · 2026Article
- Sarcopenia and Walking Recovery in Older Adults: A Mini-Review of Evidence and Rehabilitation Implications.Journal of clinical medicine · 2026Review
- Reference values for relative sit-to-stand power in Chinese middle-aged and older adults.The journal of nutrition, health & aging · 2026Article
- Integration of sarcopenia screening into radiotherapy planning: Validation of a time-efficient SMI measurement method using MIM software in prostate cancer.Journal of applied clinical medical physics · 2026Article
- Identification of ultrasound predictors and development of a diagnostic scoring system for sarcopenia using LASSO regression: a cross-sectional study.Scientific reports · 2026Article
- Association between TMG-derived contractile muscle parameters and MRI-based muscle structure in sarcopenia.BMC musculoskeletal disorders · 2026Article
- Article
- The role of sarcopenia in all-cause mortality prediction among community-dwelling adults with eGFR 15-89 mL/min/1.73 mOpen medicine (Warsaw, Poland) · 2026Article
- The joint association of obesity and low handgrip strength with cognitive impairment and probable dementia: a cross-sectional study.Frontiers in nutrition · 2026Article
- SARC-T a new physical test for sarcopenia assessment with development, validation and physiological evaluation.Frontiers in aging · 2026Article
- Defining frailty using a modified Fried's Frailty Phenotype in a Southern African context.PloS one · 2026Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 19 institutions in 7 countries.
Funding
Abstract
backgroundThe 2019 European Working Group on Sarcopenia in Older People (EWGSOP2) and the Sarcopenia Definitions and Outcomes Consortium (SDOC) have recently proposed sarcopenia definitions. However, comparisons of the performance of these approaches in terms of thresholds employed, concordance in individuals and prediction of important health-related outcomes such as death are limited. We addressed this in a large multinational assembly of cohort studies that included information on lean mass, muscle strength, physical performance and health outcomes.
methodsWhite men from the Health Aging and Body Composition (Health ABC) Study, Osteoporotic Fractures in Men (MrOS) Study cohorts (Sweden, USA), the Hertfordshire Cohort Study (HCS) and the Sarcopenia and Physical impairment with advancing Age (SarcoPhAge) Study were analysed. Appendicular lean mass (ALM) was ascertained using DXA; muscle strength by grip dynamometry; and usual gait speed over courses of 2.4-6 m. Deaths were recorded and verified. Definitions of sarcopenia were as follows: EWGSOP2 (grip strength <27 kg and ALM index <7.0 kg/m
resultsMean (SD) age of participants (n = 9170) was 74.3 (4.9) years; 5929 participants died during a mean (SD) follow-up of 12.1 (5.5) years. The proportion with sarcopenia according to each definition was EWGSOP2 (1.1%), SDOC (1.7%) and Modified SDOC (5.3%). Agreement was weak between EWGSOP2 and SDOC (κ = 0.17). Pooled hazard ratios (95% CI) for mortality for presence versus absence of each definition were EWGSOP2 [1.76 (1.42, 2.18), I
conclusionsThere was low prevalence and poor agreement among recent sarcopenia definitions in community-dwelling cohorts of older white men. All indices of sarcopenia were associated with mortality. The strong relationship between sarcopenia and mortality, regardless of the definition, illustrates that identification of appropriate management and lifecourse intervention strategies for this condition is of paramount importance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.