Evidence map›Paper›PMID 36604815›Full record

ArticleGlobal spine journal2024

Living with a C2-Sacrum Spinal Fusion: Surgical Outcomes and Quality of Life in Patients Fused from C2 to the Sacrum.

Justin Mathew, Scott L Zuckerman, Hannah Lin, Gerard Marciano, Matthew Simhon, Meghan Cerpa, Nathan J Lee, Venkat Boddapati, Ronald A Lehman, Zeeshan M Sardar and 3 more

Abstract read
In one paragraph

Article in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Justin MathewDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.ORCID 0000-0002-7699-780X
Scott L ZuckermanDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Hannah LinDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.ORCID 0000-0003-0137-7515
Gerard MarcianoDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Matthew SimhonDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Meghan CerpaDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Nathan J LeeDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.ORCID 0000-0001-9572-5968
Venkat BoddapatiDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Ronald A LehmanDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Zeeshan M SardarDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Marc D DyrszkaDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Joseph M LombardiDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.
Lawrence G LenkeDepartment of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSingle center, retrospective cohort study.

objectivesLittle is known about the surgical outcomes and quality of life in patients with C2-sacrum posterior spinal fusion (PSF). Though it is thought to be a "final" construct, it remains unknown how patients fare postoperatively. We sought to evaluate the surgical outcomes and quality of life of patients after C2-sacrum PSF.

methodsConsecutive patients undergoing C2-Sacrum PSF from 2015-2020 by 4 surgeons at a single institution were included. The study time period for each patient began after their index operation that led to the C2-sacrum fusion. Dates of surgery, complications, reoperations, patient reported outcomes (PROs) including EuroQol 5 Dimensions (EQ-5D), Oswestry Disability Index (ODI), Scoliosis Research Society (SRS) questionnaires, and activities of daily living (ADL) questions were collected and analyzed. Descriptive statistics, paired t-tests, student t-tests, and linear regression were used.

resultsOf the 23 patients who underwent C2-sacrum PSF, 6 patients (26%) required a total of 10 reoperations after a mean of 1.5 years (range 0-4 years) after C2-sacrum PSF. Five reoperations were for mechanical failure; 3 for wound complications/infection; and 2 for instrumentation and spinous process prominence. PROs were collected on 18 patients with mean follow-up of 2.4 years (range .5-4.5) after their C2-sacrum PSF. At 6-months, both SRS-22 and ODI scores improved significantly after C2-sacrum PSF (SRS: 57.5 to 76.3,

conclusionThough C2-sacrum PSF is thought to be a "final" construct, approximately 1 in 4 patients require subsequent operations. However, C2-sacrum PSF patients had a significant improvement in SRS and ODI scores by 6 months postop. Over 60% of patients were regularly performing light aerobic activity 2 years after their C2-sacrum PSF. EQ-5D suggests that this population fares better than those with degenerative hip/knee arthritis and similarly to those with common chronic conditions like DM and HTN.

Indexed as

activities of daily livingC2-sacrumfusionoutcomespatient reported outcomesPROsquality of lifereoperationsacrumsurgical outcomes

Identifiers

PMID36604815
PMCPMC11394517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.