Evidence map›Paper›PMID 36604798›Full record

ArticleIntegrative cancer therapies

Role of Traditional Chinese Medicine Syndrome Type, Gut Microbiome, and Host Immunity in Predicting Early and Advanced Stage Colorectal Cancer.

Yunzi Yan, Yufei Yang, Chunhui Ning, Na Wu, Shaohua Yan, Lingyun Sun

Abstract read
In one paragraph

Article in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yunzi YanBeijing University of Chinese Medicine, Beijing, China.ORCID 0000-0003-0507-7616
Yufei YangBeijing University of Chinese Medicine, Beijing, China.
Chunhui NingChina Academy of Chinese Medical Science, Beijing, China.
Na WuBeijing University of Chinese Medicine, Beijing, China.
Shaohua YanBeijing University of Chinese Medicine, Beijing, China.ORCID 0000-0002-3339-3184
Lingyun SunChina Academy of Chinese Medical Science, Beijing, China.ORCID 0000-0002-7191-6177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the role of Traditional Chinese Medicine (TCM) syndrome type, gut microbiome distribution, and host immunity function in predicting the early and advanced clinical stages of colorectal cancer (CRC).

methodsA cross-sectional case-control study was performed which included 48 early stage and 48 advanced patients with CRC enrolled from March 2018 to December 2020. 16S rRNA gene sequencing was performed to analyze the gut microbiomes of the patients, while T and B lymphocyte subsets in peripheral blood were assessed using flow cytometry. TCM syndrome type was measured using the spleen deficiency syndrome (SDS) scale.

resultsThe abundance levels of

conclusionOur study suggested associations between clinical stage, SDS, gut microbiota, and T lymphocytes, which provided insights for a potential prediction model for the disease progression of CRC.

Indexed as

Colorectal NeoplasmsGastrointestinal MicrobiomeCase-Control StudiesCross-Sectional StudiesHumansMedicine, Chinese TraditionalRNA, Ribosomal, 16SRNA, Ribosomal, 16Sclinical stagecolorectal cancergut microbiomeT cell immunitytraditional Chinese medicine syndrome

Identifiers

PMID36604798
PMCPMC9830091

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.