Evidence map›Paper›PMID 36604663›Full record

ArticleMalaria journal2023

Malaria among children under 10 years in 4 endemic health areas in Kisantu Health Zone: epidemiology and transmission.

Gillon Ilombe, Junior Rika Matangila, Aimee Lulebo, Paulin Mutombo, Sylvie Linsuke, Vivi Maketa, Baby Mabanzila, Francis Wat'senga, Wim Van Bortel, Agossa Fiacre and 3 more

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Article in Malaria journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Gillon IlombeUnit of Entomology, Department of Parasitology, National Institute of Biomedical Research, Kinshasa, Democratic Republic of the Congo. gillonilombe@yahoo.fr.
Junior Rika MatangilaDepartment of Tropical Medicine, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Aimee LuleboFaculty of Medicine, Public Health School, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Paulin MutomboFaculty of Medicine, Public Health School, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Sylvie LinsukeGlobal Health Institute, Antwerp University, Antwerp, Belgium.
Vivi MaketaDepartment of Tropical Medicine, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Baby MabanzilaDepartment of Tropical Medicine, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Francis Wat'sengaUnit of Entomology, Department of Parasitology, National Institute of Biomedical Research, Kinshasa, Democratic Republic of the Congo.
Wim Van BortelUnit of Entomology and Outbreak Research Team, Unit of Entomology, Institute of Tropical Medicine, Antwerp, Belgium.
Agossa FiacrePMI VectorLink Project, Abt Associates, Kinshasa, Democratic Republic of the Congo.
Seth R IrishDivision of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, President's Malaria Initiative and Entomology Branch, Atlanta, GA, USA.
Pascal LutumbaDepartment of Tropical Medicine, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jean-Pierre Van GeertruydenGlobal Health Institute, Antwerp University, Antwerp, Belgium.
University of Kinshasa · CDUniversity of Antwerp · BECenter for Global Health · USInstituut voor Tropische Geneeskunde · BENational Institute of Biomedical Research · CD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Democratic Republic of the Congo (DRC) is the second most malaria-affected country in the world with 21,608,681 cases reported in 2019. The Kongo Central (KC) Province has a malaria annual incidence of 163 cases/per 1000 inhabitants which are close to the national average of 153.4/1000. However, the malaria prevalence varies both between and within health zones in this province. The main objective of this study was to describe the epidemiology and transmission of malaria among children aged 0 to 10 years in the 4 highest endemic health areas in Kisantu Health Zone (HZ) of KC in DRC.

methodsA community-based cross-sectional study was conducted from October to November 2017 using multi-stage sampling. A total of 30 villages in 4 health areas in Kisantu HZ were randomly selected. The prevalence of malaria was measured using a thick blood smear (TBS) and known predictors and associated outcomes were assessed. Data are described and association determinants of malaria infection were analysed.

resultsA total of 1790 children between 0 and 10 years were included in 30 villages in 4 health areas of Kisantu HZ. The overall prevalence in the study area according to the TBS was 14.8% (95% CI: 13.8-16.6; range: 0-53). The mean sporozoite rate in the study area was 4.3% (95% CI: 2.6-6.6). The determination of kdr-west resistance alleles showed the presence of both L1014S and L1014F with 14.6% heterozygous L1014S/L1014F, 84.4% homozygous 1014F, and 1% homozygous 1014S. The risk factors associated with malaria infection were ground or wooden floors aOR: 15.8 (95% CI: 8.6-29.2), a moderate or severe underweight: 1.5 (1.1-2.3) and to be overweight: 1.9 (95% CI: 1.3-2.7).

conclusionMalaria prevalence differed between villages and health areas within the same health zone. The control strategy activities must be oriented by the variety in the prevalence and transmission of malaria in different areas. The policy against malaria regarding long-lasting insecticidal nets should be based on the evidence of metabolic resistance.

Indexed as

InsecticidesMalariaChildCross-Sectional StudiesDemocratic Republic of the CongoHumansPrevalenceRisk FactorsInsecticidesDemocratic Republic of the CongoDeterminantsKisantuMalaria infection

Identifiers

PMID36604663
PMCPMC9814333
OpenAlexW4313559977

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.