ArticleScientific reports2023
Exposure to polystyrene microplastic beads causes sex-specific toxic effects in the model insect Drosophila melanogaster.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 73 citations in OpenAlex.
- Article
- Microplastics induce mitochondrial dysfunction and accelerate cardiovascular pathogenesis.Archives of toxicology · 2026Review
- Preliminary Assessment of the Possible Environmental Risks of Photopolymerizing Resin Particles Produced by Finishing Stereolithography 3D-Printed Objects, Employing Toxicity Test on Tropical House Crickets (International journal of molecular sciences · 2025Article
- Metabolic effects of dietary exposure to polystyrene microplastic and nanoplastic in fruit flies.The Journal of experimental biology · 2025Article
- Ameliorative role of Polyscias fruticosa leaf extract in aluminum chloride-induced neurotoxicity flies possibly mediated by N-methyl-D-aspartate receptor antagonistic and anticholinesterase active compounds.Journal of natural medicines · 2025Article
- Label-Free Identification and Imaging of Microplastic and Nanoplastic Biouptake Using Optical Photothermal Infrared Microspectroscopy.Environmental science & technology · 2025Article
- Impact of Polystyrene Micro- and Nanoplastics on the Biological Traits of the Japanese Carpenter Ant,Insects · 2025Article
- Investigating the neuroprotective effects of strawberry extract against diesel soot-induced motor dysfunction in Drosophila: an in-vivo and in-silico study.In silico pharmacology · 2025Article
- Independent and synergistic effects of microplastics and endocrine-disrupting chemicals on the reproductive social behavior of fathead minnows (Ecology and evolution · 2024Article
- The heart of plastic: utilizing theFrontiers in toxicology · 2024Article
- Perspectives on the Drosophila melanogaster Model for Advances in Toxicological Science.Current protocols · 2023Review
- Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The toxicity of MPs on aquatic creatures has been extensively studied, but little attention was paid to terrestrial organisms. To fill this gab, we conducted a series of experiments using Drosophila as a model organism to understand whether exposure to different concentrations (0.005, 0.05, 0.5 µg/ml) of polystyrene microplastics (PS-MPs) beads (2 µm in size) can impact flies feeding activity, digestion and excretion. The ability of flies to distinguish between normal and PS-MPs treated food media was tested first, and then we evaluated the effects of a 7-day short-term exposure to PS-MPs on food intake, mortality, starvation resistance, fecal pellet count, and the cellular structure of mid gut cells. The results revealed that flies can really differentiate and ignore MPs-treated food. We discovered sex-specific effects, with male flies being more sensitive to PS-MPs, with all males dying after 14 days when exposed to 0.5 µg/ml of PS-MPs, whereas female flies survived more. All male flies exposed to PS-MPs died after 24 h of starvation. Midgut cells showed concentration-dependent necrosis and apoptosis in response to PS-MPs. Our findings provide new insights into MPs toxicity on terrestrial organisms and giving a warning that management measures against MPs emission must be taken.
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